Results 11 to 20 of about 1,457,914 (292)

Neuroinflammation and Brain Disease. [PDF]

open access: yesBMC Neurol, 2023
AbstractStarting from the perspective of an immune-privileged site, our knowledge of the inflammatory processes within the central nervous system has increased rapidly over the last 30 years, leading to a rather puzzling picture today. Of particular interest is the emergence of disease- and injury-specific inflammatory responses within the brain, which
Bersano A, Engele J, Schäfer MKE.
europepmc   +4 more sources

Pyogenic Brain Disease [PDF]

open access: greenAnnals of Otology, Rhinology & Laryngology, 1897
n ...
Albert Rufus Baker
openalex   +4 more sources

Reprogramming the diseased brain [PDF]

open access: yesNature Biotechnology, 2017
Direct conversion of astrocytes to dopamine neurons in vivo offers fresh optimism for the development of improved Parkinson's ...
Stephen B. Dunnett   +1 more
openaire   +3 more sources

Is Alzheimer’s Disease a Liver Disease of the Brain? [PDF]

open access: yesJournal of Alzheimer's Disease, 2020
Clinical specialization is not only a force for progress, but it has also led to the fragmentation of medical knowledge. The focus of research in the field of Alzheimer's disease (AD) is neurobiology, while hepatologists focus on liver diseases and lipid specialists on atherosclerosis.
Margaret Bassendine   +6 more
openaire   +5 more sources

Aquaporin and brain diseases [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - General Subjects, 2014
The presence of water channel proteins, aquaporins (AQPs), in the brain led to intense research in understanding the underlying roles of each of them under normal conditions and pathological conditions.In this review, we summarize some of the recent knowledge on the 3 main AQPs (AQP1, AQP4 and AQP9), with a special focus on AQP4, the most abundant AQP ...
Klaus G. Petry   +4 more
openaire   +3 more sources

Exploiting the aggregation propensity of beta-lactamases to design inhibitors that induce enzyme misfolding

open access: yesNature Communications, 2023
There is an arms race between beta-lactam antibiotics development and co-evolving beta-lactamases, which provide resistance by breaking down beta-lactam rings.
Ladan Khodaparast   +13 more
doaj   +1 more source

Contribution of Axon Initial Segment Structure and Channels to Brain Pathology

open access: yesCells, 2023
Brain channelopathies are a group of neurological disorders that result from genetic mutations affecting ion channels in the brain. Ion channels are specialized proteins that play a crucial role in the electrical activity of nerve cells by controlling ...
Juan José Garrido
doaj   +1 more source

"It's a brain disease" [PDF]

open access: yesPsychiatric Services, 1997
T elling me that I have a brain disease and that I should take medication does not solve my problems. When I was first given the label of “psychotic,” I’m not sure it really mattered to me what had caused it. What I heard was you telling me that I had a chronic disease.
openaire   +3 more sources

RNAs in Brain and Heart Diseases [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
In the era of single-cell analysis, one always has to keep in mind the systemic nature of various diseases and how these diseases could be optimally studied. Comorbidities of the heart in neurological diseases as well as of the brain in cardiovascular diseases are prevalent, but how interactions in the brain–heart axis affect disease development and ...
Beis, Dimitris   +9 more
openaire   +4 more sources

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