Results 11 to 20 of about 2,638,617 (370)

Multi-Perspective Feature Extraction and Fusion Based on Deep Latent Space for Diagnosis of Alzheimer’s Diseases

open access: yesBrain Sciences, 2022
Resting-state functional magnetic resonance imaging (rs-fMRI) has been used to construct functional connectivity (FC) in the brain for the diagnosis and analysis of brain disease.
Libin Gao   +6 more
doaj   +1 more source

Identification of genomic enhancers through spatial integration of single‐cell transcriptomics and epigenomics

open access: yesMolecular Systems Biology, 2020
Single‐cell technologies allow measuring chromatin accessibility and gene expression in each cell, but jointly utilizing both layers to map bona fide gene regulatory networks and enhancers remains challenging.
Carmen Bravo González‐Blas   +13 more
doaj   +1 more source

Systems modeling of white matter microstructural abnormalities in Alzheimer's disease [PDF]

open access: yes, 2020
INTRODUCTION: Microstructural abnormalities in white matter (WM) are often reported in Alzheimer's disease (AD). However, it is unclear which brain regions have the strongest WM changes in presymptomatic AD and what biological processes underlie WM ...
Alzheimer's Disease Neuroimaging Initiative (ADNI)   +9 more
core   +1 more source

An overview of seizures and epilepsy in rabbits: etiological differences and clinical management [PDF]

open access: yesНауковий вісник ветеринарної медицини, 2021
World Health Organization data suggest that neurological disorders are an important and growing cause of morbidity. One of the most common neurological disorder affecting people is epilepsy. Many companion animal neurological diseases share epidemiologic,
Gülersoy E., İyigün S.S., Erol B.B.
doaj   +1 more source

Is Alzheimer’s Disease a Liver Disease of the Brain? [PDF]

open access: yesJournal of Alzheimer's Disease, 2020
Clinical specialization is not only a force for progress, but it has also led to the fragmentation of medical knowledge. The focus of research in the field of Alzheimer's disease (AD) is neurobiology, while hepatologists focus on liver diseases and lipid specialists on atherosclerosis.
Margaret Bassendine   +6 more
openaire   +5 more sources

Dual mechanism of brain injury and novel treatment strategy in maple syrup urine disease [PDF]

open access: yes, 2009
Maple syrup urine disease (MSUD) is an inherited disorder of branched-chain amino acid metabolism presenting with lifethreatening cerebral oedema and dysmyelination in affected individuals.
Ara  jo   +44 more
core   +2 more sources

Aquaporin and brain diseases [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - General Subjects, 2014
The presence of water channel proteins, aquaporins (AQPs), in the brain led to intense research in understanding the underlying roles of each of them under normal conditions and pathological conditions.In this review, we summarize some of the recent knowledge on the 3 main AQPs (AQP1, AQP4 and AQP9), with a special focus on AQP4, the most abundant AQP ...
Klaus G. Petry   +4 more
openaire   +3 more sources

THE PSYCHOMOTOR THEORY OF HUMAN MIND [PDF]

open access: yes, 2007
This study presents a new theory to explain the neural origins of human mind. This is the psychomotor theory. The author briefly analyzed the historical development of the mind-brain theories.
TAN, Prof. Dr. Uner
core   +1 more source

Identification and in vivo characterization of a brain-penetrating nanobody

open access: yesFluids and Barriers of the CNS, 2020
Background Preclinical models to determine blood to brain transport ability of therapeutics are often ambiguous. In this study a method is developed that relies on CNS target-engagement and is able to rank brain-penetrating capacities. This method led to
Y Wouters   +3 more
doaj   +1 more source

Structural network efficiency is associated with cognitive impairment in small-vessel disease. [PDF]

open access: yes, 2014
To characterize brain network connectivity impairment in cerebral small-vessel disease (SVD) and its relationship with MRI disease markers and cognitive impairment.METHODS: A cross-sectional design applied graph-based efficiency analysis to deterministic
Barrick, TR   +4 more
core   +2 more sources

Home - About - Disclaimer - Privacy