Results 81 to 90 of about 13,615,192 (223)

Glucose transporters in brain in health and disease

open access: yesPflügers Archiv: European Journal of Physiology, 2020
Energy demand of neurons in brain that is covered by glucose supply from the blood is ensured by glucose transporters in capillaries and brain cells.
H. Koepsell
semanticscholar   +1 more source

Phosphoinositides: Regulators of Nervous System Function in Health and Disease

open access: yesFrontiers in Molecular Neuroscience, 2019
Phosphoinositides, the seven phosphorylated derivatives of phosphatidylinositol have emerged as regulators of key sub-cellular processes such as membrane transport, cytoskeletal function and plasma membrane signaling in eukaryotic cells.
Padinjat Raghu   +4 more
doaj   +1 more source

Altered GABAergic Signaling in Brain Disease at Various Stages of Life

open access: yesExperimental Neurobiology, 2017
In the healthy brain, gamma-aminobutyric acid (GABA) is regulated by neurons and glia. This begs the question: what happens in the malfunctioning brain?
Y. Kim, Bo-Eun Yoon
semanticscholar   +1 more source

Structure-based machine-guided mapping of amyloid sequence space reveals uncharted sequence clusters with higher solubilities

open access: yesNature Communications, 2020
An increasing number of amyloid structures are determined. Here, the authors present the structure-based amyloid core sequence prediction method Cordax that is based on machine learning and allows the detection of aggregation-prone regions with higher ...
Nikolaos Louros   +4 more
doaj   +1 more source

Early diagnosis of Alzheimer's disease: update on combining genetic and brain-imaging measures. [PDF]

open access: yes, 2000
Diagnosis of Alzheimer's disease is often missed or delayed in clinical practice; thus, methods to improve early detection would provide opportunities for early intervention, symptomatic treatment, and improved patient function.
Small, GW
core   +1 more source

Editorial: Advances in brain functional and structural networks modeling via graph theory

open access: yesFrontiers in Neuroscience, 2022
Farras Abdelnour   +4 more
doaj   +1 more source

Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer

open access: yesNature Communications, 2020
Mossy fiber synapses are key in CA3 microcircuit function. Here, the authors profile the mossy fiber synapse proteome and cell-surface interactome. They uncover a diverse repertoire of cell-surface proteins and identify the receptor IgSF8 as a regulator ...
Nuno Apóstolo   +13 more
doaj   +1 more source

Editorial: Computational Neuroimage Analysis Tools for Brain (Diseases) Biomarkers

open access: yesFrontiers in Neuroscience, 2022
Diana M. Sima   +8 more
doaj   +1 more source

Dasatinib regulates LPS-induced microglial and astrocytic neuroinflammatory responses by inhibiting AKT/STAT3 signaling

open access: yesJournal of Neuroinflammation, 2019
Background The FDA-approved small-molecule drug dasatinib is currently used as a treatment for chronic myeloid leukemia (CML). However, the effects of dasatinib on microglial and/or astrocytic neuroinflammatory responses and its mechanism of action have ...
Ka-Young Ryu   +11 more
doaj   +1 more source

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