Results 151 to 160 of about 8,895 (193)

More Than Just a Floppy Baby: Maintaining High Clinical Suspicion of Infant Botulism. [PDF]

Cureus
Sarintra N, Ekdahl R, Sanders SC, Slagle B, Tang K.   +4 more
europepmc   +1 more source

Maternal glycaemia and child educational attainment at age 5 in the Born in Bradford cohort

Diabetic Medicine, EarlyView.
Abstract Aims There is emerging evidence that maternal hyperglycaemia may be associated with adverse offspring neuro‐behavioural outcomes, which are foundational to educational success. We hypothesised that higher levels of maternal glucose would be associated with poorer educational attainment in early childhood.
Claire A. Wilson, Gillian Santorelli, Emily Simonoff, Louise M. Howard, Khalida Ismail, Rebecca M. Reynolds   +5 more
wiley   +1 more source

Seizures and Apneas as clinical manifestations of brain lesions in term infants: a single center experience. [PDF]

Ital J Pediatr
Skubisz A, Calandrino A, Vinci F, Massirio P, Andreato C, Caruggi S, Battaglini M, Parodi A, Brigati G, Malova M, Bertamino M, Tortora D, Severino M, Resaz M, Amadori E, Uccella S, Nobili L, Rossi A, Striano P, Ramenghi LA.   +19 more
europepmc   +1 more source

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

European Journal of Haematology, EarlyView.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

The inhibitors of 17β-HSD10: are they any good? [PDF]

RSC Chem Biol
Kwa E, Ogilvie CE, Kormos NC, Green AJE, Smith TK, Gunn-Moore FJ.   +5 more
europepmc   +1 more source

Shikimate pathway disruption in yeast induces metabolite self‐assembly into toxic aggregates

The FEBS Journal, EarlyView.
In Saccharomyces cerevisiae, shikimate pathway disruption induces toxic metabolite assemblies. Deleting ARO4 plus phenylalanine (Phe) feeding causes Phenylalanine accumulation, lowers ARO3 activity, and triggers amyloid‐like fibril formation. Deleting ARO3 plus tyrosine (Tyr) feeding leads to Tyrosine buildup and similar fibril assembly.
Hanaa Adsi, Myra Gartner, Claris Simovich, Lihi Gershon, Alexander Brandis, Ehud Gazit, Dana Laor Bar‐Yosef   +6 more
wiley   +1 more source

Air-liquid interface-centered oxygen engineering in human brain organoids: intact, sliced, and microfluidic extensions. [PDF]

Front Cell Dev Biol
Vijakumaran U, Anjum A, Devaraju P, Abd Razak NH, Daud MF, Mohd Idris I.   +5 more
europepmc   +1 more source

Laboratory and Medicine 2.1: Care for What You Wish for

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Over the past few decades, healthcare has made remarkable advances. Across nearly all fields, diseases are better understood, and diagnostic and therapeutic options have expanded dramatically. Laboratory medicine is also developing at a rapid pace and is playing an increasingly central role in the diagnostic process, as well as in the ...
Marcel Levi
wiley   +1 more source

Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review. [PDF]

J Inherit Metab Dis
Jaeger B, Stolwijk NN, Aaldering F, Ruys CA, Smits M, Wolf NI, Hollak CEM, Bosch AM.   +7 more
europepmc   +1 more source