Results 251 to 260 of about 188,500 (303)
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Edema and brain trauma

Neuroscience, 2004
Brain edema leading to an expansion of brain volume has a crucial impact on morbidity and mortality following traumatic brain injury (TBI) as it increases intracranial pressure, impairs cerebral perfusion and oxygenation, and contributes to additional ischemic injuries.
A W Unterberg, B Kress
exaly   +3 more sources

Aquaporins in brain edema

Journal of Neuroscience Research, 2018
AbstractBrain edema is a common feature of brain injuries, which leads to increased intracranial pressure (ICP) and ischemia that worsen outcome. Current management of edema focuses on reduction of ICP, but there are no treatments targeting the molecular players directly involved in edema process.
Tifenn Clément   +2 more
openaire   +2 more sources

Aquaporins and brain edema

Surgical Neurology, 2004
Aquaporins are a family of transmembrane proteins that selectively allow the passage of water through the plasma membrane. Their importance is highlighted by their ubiquitous presence from bacteria to mammals. In humans, they are found throughout the body and recent work has highlighted their function within the brain.
Donald E G, Griesdale   +1 more
openaire   +2 more sources

Experimental Brain Edema

Archives of Neurology, 1970
IT HAS BEEN suggested in a previous paper 1 that the biological function of the mitochondria in brain tissue decreases in association with the initiation and the development of brain edema. The mechanism of the impairment in mitochondrial function has been partially elucidated by many workers in the general biochemical field.
M, Yamaguchi   +3 more
openaire   +2 more sources

The management of brain edema in brain tumors

Current Opinion in Oncology, 2004
This review focuses on pathophysiology, clinical signs, and imaging of brain edema associated with intracranial tumors and its treatment. Brain edema in brain tumors is the result of leakage of plasma into the parenchyma through dysfunctional cerebral capillaries.
Evert C A, Kaal, Charles J, Vecht
openaire   +2 more sources

Ischemic brain edema

Progress in Cardiovascular Diseases, 1999
Brain edema is a life-threatening complication of cerebral infarction. The molecular cascade initiated by cerebral ischemia includes the loss of membrane ionic pumps and cell swelling. Secondary formation of free radicals and proteases disrupts brain-cell membranes, causing irreversible damage. New diagnostic methods based on magnetic resonance imaging
openaire   +2 more sources

Brain Edema

1986
Current concepts on the development of brain edema are briefly reviewed. The common classification into vasogenic and cytotoxic edema is a simplification and does not cover all types of edema. Alternative routes of edema resolution are discussed. More basic data on the mechanisms of development and regression of brain edema are needed before more ...
openaire   +2 more sources

Pathophysiological aspects of brain edema

Acta Neuropathologica, 1972
Two mayor types of brain edema, related to two different pathomechanisms, can be recognized: 1) cytotoxic type-where the main feature is the swelling of cellular elements of brain parenchyma and 2) vasogenic type-where an increased vascular permeability leading to accumulation of edema fluid in the extracellular spaces plays the principal role. In this
openaire   +2 more sources

Blood–brain barrier and brain edema

2012
Abstract The function of the blood–brain barrier (BBB) continues to be a diagnostic and therapeutic challenge for physicians treating patients with central nervous system (CNS) malignancies. Despite its physiological importance, only a few clinical studies have specifically addressed the role of the BBB in the biology of brain tumors.
Michael, Platten, Wolfgang, Wick
openaire   +2 more sources

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