Results 81 to 90 of about 6,609,276 (156)

Sema7A/PlxnCl signaling triggers activity-dependent olfactory synapse formation

Nature Communications, 2018
The molecular mechanisms underlying synapse formation in the olfactory bulb are not fully understood. Here the authors demonstrate that semaphorin 7A on olfactory sensory neurons, and its receptor plexin C1 expressed on mitral and tufted cells, is ...
Nobuko Inoue, Hirofumi Nishizumi, Hiromi Naritsuka, Hiroshi Kiyonari, Hitoshi Sakano   +4 more
doaj   +1 more source

Behavioral characterization of early nicotine withdrawal in the mouse: a potential model of acute dependence

Behavioral and Brain Functions
Background Clinical and preclinical research have demonstrated that short-term exposure to nicotine during the initial experimentation stage can lead to early manifestation of withdrawal-like signs, indicating the state of “acute dependence”.
Baeksun Kim, Heh-In Im
doaj   +1 more source

Delta coherence in resting-state EEG predicts the reduction in cigarette craving after hypnotic aversion suggestions

Scientific Reports, 2017
Cigarette craving is a key contributor of nicotine addiction. Hypnotic aversion suggestions have been used to help smoking cessation and reduce smoking relapse rates but its neural basis is poorly understood. This study investigated the underlying neural
Xiaoming Li, Ru Ma, Liangjun Pang, Wanwan Lv, Yunlu Xie, Ying Chen, Pengyu Zhang, Jiawen Chen, Qichao Wu, Guanbao Cui, Peng Zhang, Yifeng Zhou, Xiaochu Zhang   +12 more
doaj   +1 more source

Phase dependent modulation of tremor amplitude in essential tremor through thalamic stimulation [PDF]

, 2013
High frequency deep brain stimulation of the thalamus can help ameliorate severe essential tremor. Here we explore how the efficacy, efficiency and selectivity of thalamic deep brain stimulation might be improved in this condition.
Green, Alexander L, Zrinzo, L, Brittain, John-Stuart, Green, Alexander L., Aziz, Tipu, Green, AL, Zrinzo, Ludvic, Little, S, Cagnan, H, Little, Simon, Limousin, P, Fitzgerald, James, Cagnan, Hayrire, Foltynie, Thomas, Hariz, Marwan, Brittain, JS, Limousin, Patricia, Aziz, T, Brown, Peter, Joint, Carole, Fitzgerald, J, Hariz, M, Cagnan, Hayriye, Foltynie, T, Brown, P, Green, Alexander, Joint, C   +26 more
core   +1 more source

Cell-based regenerative and rejuvenation strategies for treating neurodegenerative diseases

Stem Cell Research & Therapy
Neurodegenerative diseases including Alzheimer’s and Parkinson’s disease are age-related disorders which severely impact quality of life and impose significant societal burdens. Cellular senescence is a critical factor in these disorders, contributing to
Sixiu Deng, Huangfan Xie, Bingqing Xie
doaj   +1 more source

Investigating severe pediatric traumatic brain injury in South Africa : a demographic profile of admissions, brain oxygenation and neuropsychological outcomes and an attention-training intervention [PDF]

, 2013
Includes bibliographical references.The aim of this dissertation was to investigate severe pediatric traumatic brain injury (pTBI) in South Africa. To that end, I conducted three studies, each examining a different aspect of severe pTBI. Study 1 presents
Schrieff, Leigh
core   +1 more source

Molecular signatures and lineage diversification of neurogenic and gliogenic radial glia in the gyrencephalic ferret cortex

Communications Biology
Human exceptional cognition stems from evolutionarily derived cortical adaptations that drive expansive neurogenesis. In this study, we employ the gyrencephalic ferret model to systematically characterize the molecular profiles and lineage dynamics of ...
Jialin Li, Feihong Yang, Weiwei Li, Tongye Fu, Zhenmeiyu Li, Zizhuo Sha, Wenhui Zheng, Chuannan Yang, Jingzhe Yu, Danyu Han, Xin Jiang, Yan You, Xiaosu Li, Tong Ma, Miao He, Zhejun Xu, Xiaolei Song, Bin Chen, Jing Ding, Xin Wang, Zhuangzhi Zhang, Zhengang Yang   +21 more
doaj   +1 more source

RpiBeh offers a versatile open source solution for rodent behavior tracking and closed loop interventions

Scientific Reports
High-precision behavior tracking and closed-loop intervention are essential for studying the neural basis of cognition and behavior. Existing commercial systems are costly and inflexible for customization, while current open-source tools are often lack ...
Yiqi Sun, Jie Zhang, Qianyun Wang, Jianguang Ni   +3 more
doaj   +1 more source

Minimized Extracorporeal Circulation does not impair cognitive brain function after coronary artery bypass grafting

, 2015
Gebiet: Chirurgie Abstract: Minimized Extracorporeal Circulation does not impair cognitive brain function after coronary artery bypass grafting – – Objectives – Objective evaluation of the impact of minimized extracorporeal circulation (MECC) on ...
Winkler, Bernhard
core  

Neuromodulator Dynamics Underlying Associative Learning in the Ventral Striatum's Olfactory Tubercle

Advanced Science
The brain's neuromodulatory systems—particularly dopamine (DA), serotonin (5‐HT), acetylcholine (ACh), and norepinephrine (NE)—play a crucial role in reward processing and associative learning. The olfactory tubercle (OT), a region that overlaps with the
Maojun Hong, Liuting Zou, Yiqing Chen, Juan Guo, Zhixiang Xu, Tong Ma, Shuaishuai Hu, Rongfeng K. Hu   +7 more
doaj   +1 more source