Results 141 to 150 of about 888,532 (366)

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

Resting state fMRI-based brain information flow mapping [PDF]

arXiv
Human brain is a massive information generation and processing machine. Studying the information flow may provide unique insight into brain function and brain diseases. We present here a tool for mapping the regional information flow in the entire brain using fMRI. Using the tool, we can estimate the information flow from a single region to the rest of
arxiv  

EEG brain mapping in evaluating the time‐course of the central action of DUP 996‐a new acetylcholine releasing drug. [PDF]

, 1989
B. Saletu, A. Darragh, Paul M. Salmon, Robert F. Coen   +3 more
openalex   +1 more source

Plasma Brain Dynamics (PBD): II. Quantum Effects on Consciousness [PDF]

, 2018
This article studies the quantum effect of the brain neuronal system on both normal and abnormal conscious states. It develops Plasma Brain Dynamics (PBD) to obtain a set of kinetic quantum-plasma Wigner-Poisson equations.
Ma, John Z. G.
core  

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Fronto-Temporal Connectivity Predicts ECT Outcome in Major Depression

Frontiers in Psychiatry, 2018
BackgroundElectroconvulsive therapy (ECT) is arguably the most effective available treatment for severe depression. Recent studies have used MRI data to predict clinical outcome to ECT and other antidepressant therapies. One challenge facing such studies
Amber M. Leaver, Benjamin Wade, Megha Vasavada, Gerhard Hellemann, Shantanu H. Joshi, Randall Espinoza, Katherine L. Narr, Katherine L. Narr   +7 more
doaj   +1 more source

Individual brain parcellation: Review of methods, validations and applications [PDF]

arXiv
Individual brains vary greatly in morphology, connectivity and organization. The applicability of group-level parcellations is limited by the rapid development of precision medicine today because they do not take into account the variation of parcels at the individual level.
arxiv  

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

Evaluation of the ¹¹CO₂ Positron Emission Tomographic Method for Measuring Brain pH. II. Quantitative pH Mapping in Patients with Ischemic Cerebrovascular Diseases [PDF]

, 1989
Michio Senda, Nathaniel M. Alpert, Bruce C. Mackay, Richard B. Buxton, John A. Correia, Steven B. Weise, Robert H. Ackerman, David J. Dorer, Ferdinando S. Buonanno   +8 more
openalex   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source