Results 61 to 70 of about 786,701 (285)

A randomized open-label clinical trial on the effect of Amantadine on post Covid 19 fatigue

open access: yesScientific Reports
Many COVID-19 survivors experience lingering post-COVID-19 symptoms, notably chronic fatigue persisting for months after the acute phase. Despite its prevalence, limited research has explored effective treatments for post-COVID-19 fatigue.
Ali Amini Harandi   +9 more
doaj   +1 more source

High-density diffuse optical tomography for imaging human brain function [PDF]

open access: yes, 2019
This review describes the unique opportunities and challenges for noninvasive optical mapping of human brain function. Diffuse optical methods offer safe, portable, and radiation free alternatives to traditional technologies like positron emission ...
Culver, Joseph P   +2 more
core   +1 more source

Geometry Processing of Conventionally Produced Mouse Brain Slice Images

open access: yes, 2017
Brain mapping research in most neuroanatomical laboratories relies on conventional processing techniques, which often introduce histological artifacts such as tissue tears and tissue loss.
Agarwal, Nitin   +2 more
core   +1 more source

Brain/MINDS: brain-mapping project in Japan [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2015
There is an emerging interest in brain-mapping projects in countries across the world, including the USA, Europe, Australia and China. In 2014, Japan started a brain-mapping project called Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS). Brain/MINDS aims to map the structure and function of neuronal circuits
Okano, Hideyuki   +2 more
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Development of the Default Mode and Central Executive Networks across early adolescence: A longitudinal study

open access: yesDevelopmental Cognitive Neuroscience, 2014
The mature brain is organized into distinct neural networks defined by regions demonstrating correlated activity during task performance as well as rest.
Lauren E. Sherman   +5 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Intracranial hypertension as an initial clinical manifestation of Systemic Lupus Erythematosus

open access: yesInterdisciplinary Neurosurgery, 2019
Background: Systemic Lupus Erythematosus (SLE) is an auto-immune systemic disorder that may affect multiple organ systems including central nervous system.
Hossein Kalanie   +2 more
doaj   +1 more source

Modern Brain Mapping – What Do We Map Nowadays? [PDF]

open access: yesFrontiers in Psychiatry, 2015
The problem of function localization in the brain is one of the most fundamental in neuroscience. There are two opposite paradigms relating to the problem: “modularism,” also known as “localism,” versus “holism,” which have been discussed for a long time (1, 2). The debate in favor of one or another view can still be traced at all methodological levels
Maria eNazarova   +3 more
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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