Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Phantom Sensations: What's a Brain to Do? A Critical Review of the Re-mapping Hypothesis [PDF]
, 2018 I will review the most widely held account of phantom sensations; the “re-mapping hypothesis.” According to the re-mapping hypothesis, amputation is followed by significant neural reorganization that, over time, restores the alignment between the brain’s
DeFranco, Daniel
core
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
EEG Microstates in Altered States of Consciousness
Frontiers in Psychology, 2022 Conscious experiences unify distinct phenomenological experiences that seem to be continuously evolving. Yet, empirical evidence shows that conscious mental activity is discontinuous and can be parsed into a series of states of thoughts that manifest as ...
Lucie Bréchet +3 more
doaj +1 more source
Scalable volumetric imaging for ultrahigh-speed brain mapping at synaptic resolution
bioRxiv, 2017 We describe a new light-sheet microscopy method for fast, large-scale volumetric imaging. Combining synchronized scanning illumination and oblique imaging over cleared, thick tissue sections in smooth motion, our approach achieves high-speed 3D image ...
Hao Wang +21 more
semanticscholar +1 more source
Neurobiology of Disease, 2000 The brain has revealed many of its secrets during the decade dedicated to its honor. Many of the exquisite techniques used in quite ingenious ways to uncover the workings of the brain involve microanalysis of the chemistry and biophysics of the brain’s complex and varied cellular structure.
openaire +4 more sources
Sensory Transduction and Subjective Experience: Expression of eight genes in three senses suggests a radical model of consciousness [PDF]
, 2007 Recent research into whole genome mapping of the mouse brain has made possible direct investigation of the brain expression of unusual genes. A search of the Allen Brain Atlas database has provided genetic and neuro-anatomical evidence for widespread ...
Chris C. King
core +1 more source
A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale [PDF]
, 2009 In this era of complete genomes, our knowledge of neuroanatomical circuitry remains surprisingly sparse. Such knowledge is however critical both for basic and clinical research into brain function. Here we advocate for a concerted effort to fill this gap,
A MacKenzie-Graham +109 more
core +8 more sources
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
A randomized open-label clinical trial on the effect of Amantadine on post Covid 19 fatigue
Scientific ReportsMany COVID-19 survivors experience lingering post-COVID-19 symptoms, notably chronic fatigue persisting for months after the acute phase. Despite its prevalence, limited research has explored effective treatments for post-COVID-19 fatigue.
Ali Amini Harandi +9 more
doaj +1 more source