Results 61 to 70 of about 268,662 (315)

Visual processing deficits in 22q11.2 Deletion Syndrome

NeuroImage: Clinical, 2018
Carriers of the rare 22q11.2 microdeletion present with a high percentage of positive and negative symptoms and a high genetic risk for schizophrenia. Visual processing impairments have been characterized in schizophrenia, but less so in 22q11.2 Deletion
Marjan Biria, Miralena I. Tomescu, Anna Custo, Lucia M. Cantonas, Kun-Wei Song, Maude Schneider, Micah M. Murray, Stephan Eliez, Christoph M. Michel, Tonia A. Rihs   +9 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Prosopagnosia and the role of face-sensitive areas in race perception

Scientific Reports
Race is rapidly and effortlessly extracted from faces. Previous fMRI studies have reported race-related modulations in the bilateral Fusiform Face Areas (FFAs) and Occipital Face Areas (OFAs) during the categorization of faces by race.
Pauline Schaller, Anne-Raphaëlle Richoz, Justin Duncan, Peter de Lissa, Roberto Caldara   +4 more
doaj   +1 more source

Ten Years of BrainAGE as a Neuroimaging Biomarker of Brain Aging: What Insights Have We Gained?

Frontiers in Neurology, 2019
With the aging population, prevalence of neurodegenerative diseases is increasing, thus placing a growing burden on individuals and the whole society.
Katja Franke, Christian Gaser, Christian Gaser   +2 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Idiosyncratic fixation patterns generalize across dynamic and static facial expression recognition

Scientific Reports
Facial expression recognition (FER) is crucial for understanding the emotional state of others during human social interactions. It has been assumed that humans share universal visual sampling strategies to achieve this task.
Anita Paparelli, Nayla Sokhn, Lisa Stacchi, Antoine Coutrot, Anne-Raphaëlle Richoz, Roberto Caldara   +5 more
doaj   +1 more source

Projection-specific and reversible functional blockage in the association cortex of macaque monkeys

Neuroscience Research
The functional manipulation techniques based on optogenetics have been widely and effectively utilized in the rodent brain. However, the applications of these techniques to the macaque cerebral cortex, particularly those to the prefrontal cortex, have ...
Seiichirou Yokoo, Takayasu Higo, Florian Gerard-Mercier, Mineki Oguchi, Masamichi Sakagami, Haruhiko Bito, Masayuki Sakamoto, Noritake Ichinohe, Keiji Tanaka   +8 more
doaj   +1 more source

Mapping individual differences across brain network structure to function and behavior with connectome embedding

, 2021
Gidon Levakov, Joshua Faskowitz, Galia Avidan, Olaf Sporns   +3 more
openalex   +1 more source