Results 191 to 200 of about 182,203 (309)

Longer Acting Injectable: Continuous, Linear Release of a Progestin Contraceptive From an Oxidized Porous Silicon Host

open access: yesAdvanced Healthcare Materials, EarlyView.
Progestin drugs are loaded into a mesoporous silicon dioxide host by melt‐infiltration. Drugs that decompose at or close to their melting point can be loaded by the addition of cholesterol, which acts as a melting point suppressor. High mass loading of the drug is achieved, and dissolution of the composite is controlled by the nanoscale properties of ...
Geoffrey Hollett   +13 more
wiley   +1 more source

An In Situ Curing, Shear‐Responsive Biomaterial Designed for Durable Embolization of Microvasculature

open access: yesAdvanced Healthcare Materials, EarlyView.
NeoCast is a next‐generation, solvent‐free, non‐adhesive liquid embolic designed for indications where deep occlusion is desired (e.g., tumors and chronic subdural hematoma). This novel agent offers ideal embolic properties: injectability, controllability, excellent visibility, and biocompatibility.
Quynh P. Pham   +16 more
wiley   +1 more source

3D Microtumors Representing Ovarian Cancer Minimal Residual Disease Respond to the Fatty Acid Oxidation Inhibitor Perhexiline

open access: yesAdvanced Healthcare Materials, EarlyView.
Minimal residual disease (MRD) leads to cancer relapse and poor survival in ovarian cancer. The lack of representative 3D models limits therapy development. The microfluidics‐based high throughput 3D microtumor platform described here generates clinically‐relevant MRD models. The 3D microtumors recapitulate the molecular signatures of MRD from patients.
Xingyun Yang   +14 more
wiley   +1 more source

Apparent diffusion coefficient and Magnetic resonance spectroscopy in grading of malignant brain neoplasms

open access: diamond, 2014
Mahmoud Abd Elaziz Dawoud   +2 more
openalex   +1 more source

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

open access: yesAdvanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell   +5 more
wiley   +1 more source

Ischemic Myocardium Targeting Peptide‐Guided Nanobubbles for Multimodal Imaging and Treatment of Coronary Microvascular Dysfunction

open access: yesAdvanced Healthcare Materials, EarlyView.
Nanobubbles functionalized with indocyanine green and ischemic myocardium‐targeting peptide effectively target cardiomyocytes and enable the multimodal (fluorescence, ultrasonic, and photoacoustic) imaging of ischemic myocardium in mice with coronary microvascular dysfunction (CMD).
Bo Yu   +8 more
wiley   +1 more source

THE POSSIBILITIES OF TREATMENT OF PATIENTS WITH MALIGNANT NEOPLASMS OF THE FEMALE REPRODUCTIVE SYSTEM WITH METASTATIC BRAIN LESION

open access: diamond, 2016
A. M. Zaytsev   +4 more
openalex   +2 more sources

Biomimetic Glycosaminoglycan‐Analog Hydrogel for Improved Embolization of Aneurysms: Environment‐Selective Swelling

open access: yesAdvanced Healthcare Materials, EarlyView.
Biomimetic glycosaminoglycan analog hydrogels exhibit suitable and robust mechanical properties, as well as hemocompatibility and biocompatibility, making them ideal for the embolization of intracranial aneurysms. Notably, the hydrogel's environment‐selective swelling properties enable complete blockage of the aneurysm cavity while preventing ...
Sarit S. Sivan   +8 more
wiley   +1 more source

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