CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis [PDF]
Retinoblastoma is a pediatric eye tumor in which bi-allelic inactivation of the Retinoblastoma 1 (RB1) gene is the initiating genetic lesion. Although recently curative rates of retinoblastoma have increased, there are at this time no molecular targeted ...
Boel, Annekatrien +12 more
core +2 more sources
Clinical reasoning in canine spinal disease: what combination of clinical information is useful? [PDF]
Spinal disease in dogs is commonly encountered in veterinary practice. Numerous diseases may cause similar clinical signs and presenting histories. The study objective was to use statistical models to identify combinations of discrete parameters from the
ABRAMSON +36 more
core +3 more sources
Application of preoperative chemotherapy in pediatric brain maligant tumors patients
Objective To investigate the indication and significance of preoperative chemotherapy for pediatric patients with brain malignant tumors. Methods and Results The clinical data of 9 pediatric patients with brain malignant tumors who were admitted to ...
WANG Jun⁃hua +5 more
doaj +1 more source
Current Challenges and Future Directions in Screening for Brain Tumours
Keywords: Brain Neoplasms/diagnosis; Mass Screening.
José Luís Alves +1 more
doaj +1 more source
Interhemispheric lipoma with callosal dysgenesis [PDF]
Intracranial lipomas are uncommon benign lesions of the central nervous system. Intracranial lipomas are usually asymptomatic and an occasional finding.
Prvulović Nataša +3 more
doaj +1 more source
Two-grade metabolic tumour tissue assessment using positron emission tomography in prediction of overall survival in glioblastoma patients [PDF]
Background/Aim. Although considered rare, gliomas cause morbidity and mortality disproportionate to their incidence. The aim of the study was to determine whether pre and post-therapeutic metric values, derived from the FDG PET/CT maximal standardized ...
Lučić Silvija +7 more
doaj +1 more source
Intranasal melanoma treated with radiation therapy in three dogs [PDF]
Three dogs were investigated for chronic unilateral nasal discharge. In all cases CT imaging showed an intranasal mass causing turbinate lysis and no evidence of metastasis.
Blackwood, L +6 more
core +4 more sources
The impact of high grade glial neoplasms on human cortical electrophysiology [PDF]
ObjectiveThe brain's functional architecture of interconnected network-related oscillatory patterns in discrete cortical regions has been well established with functional magnetic resonance imaging (fMRI) studies or direct cortical electrophysiology from
Bandt, S. Kathleen +8 more
core +3 more sources
Neuroplasticity of Glioma Patients: Brain Structure and Topological Network
Glioma is the most common primary malignant brain tumor in adults. It accounts for about 75% of such tumors and occurs more commonly in men. The incidence rate has been increasing in the past 30 years. Moreover, the 5-year overall survival rate of glioma
Kun Lv +18 more
doaj +1 more source

