Results 101 to 110 of about 1,068,311 (337)

Network Properties Revealed during Multi-Scale Calcium Imaging of Seizure Activity in Zebrafish. [PDF]

, 2019
Seizures are characterized by hypersynchronization of neuronal networks. Understanding these networks could provide a critical window for therapeutic control of recurrent seizure activity, i.e., epilepsy.
Baraban, Scott C, Liu, Jing
core   +1 more source

1st European Psychoneuroimmunology Network (EPN) Autumn School: Lung-Brain Axis in Health and Disease [PDF]

, 2022

openalex   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Neural Determinants of Sedentary Lifestyle in Older Adults: A Brain Network Analysis

Brain and Behavior
Purpose The prevalence of sedentary lifestyles (SL), which includes both high volumes of extended sitting behavior and a low volume of steps accumulated across the day, among older adults continues to rise contributing to increases in associated ...
Mohsen Bahrami, Jonathan H Burdette, Paul J Laurienti, Barbara J Nicklas, W Jack Rejeski, Jason Fanning   +5 more
doaj   +1 more source

Combining EEG source connectivity and network similarity: Application to object categorization in the human brain

, 2016
A major challenge in cognitive neuroscience is to evaluate the ability of the human brain to categorize or group visual stimuli based on common features.
Dufor, Olivier, Hassan, Mahmoud, Khalil, Mohamad, Mheich, Ahmad, Wendling, Fabrice   +4 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Robotized functional localization with TMS

Brain Stimulation, 2021
Benjamin Kalloch, Ole Numssen, Thomas Knösche, Gesa Hartwigsen, Konstantin Weise   +4 more
doaj   +1 more source

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Alu-mediated RNA duplexes are associated with widespread exon skipping across primate transcriptomes

Genome Biology
Alternative splicing patterns have diverged rapidly during vertebrate evolution. By integrating genome-wide predictions of stable RNA duplexes, alternative splicing profiles, and proximity ligation-detection of RNA-RNA interactions, we observe that the ...
Hyunbeen Lee, Xinang Cao, Guillermo E. Parada, Jack Daiyang Li, Ira A. Iosub, Ulrich Braunschweig, Kenny Rebelo, Jernej Ule, Yue Wan, Benjamin J. Blencowe   +9 more
doaj   +1 more source

Application of Graph Theory for Identifying Connectivity Patterns in Human Brain Networks: A Systematic Review

Frontiers in Neuroscience, 2019
Background: Analysis of the human connectome using functional magnetic resonance imaging (fMRI) started in the mid-1990s and attracted increasing attention in attempts to discover the neural underpinnings of human cognition and neurological disorders. In
Farzad V. Farahani, Waldemar Karwowski, Nichole R. Lighthall   +2 more
doaj   +1 more source