Results 141 to 150 of about 353,480 (216)

Backbone‐Controlled Ion‐Side Chain Accessibility in Conjugated Polymers for Organic Electrochemical Synaptic Transistors

open access: yesAdvanced Functional Materials, EarlyView.
Backbone modulation in glycolated conjugated polymers governs ion accessibility to side chains, strengthes anion adsorption, and suppresses back‐diffusion. As the number of thiophene units increases, structural reorganization, retention, and synaptic plasticity are enhanced, leading to improved neuromorphic performance in electrolyte‐gated organic ...
Junho Sung   +10 more
wiley   +1 more source

Spatiotemporal Drug Delivery via a Neonatal Spinal Cord ECM Hydrogel for Biomimetic Microenvironment Remodeling After Spinal Cord Injury

open access: yesAdvanced Functional Materials, EarlyView.
A biomimetic hydrogel derived from neonatal spinal cord ECM (DNSCM) delivers LAMB2 protein and ISP peptide to remodel the inhibitory injury microenvironment. The system sustains drug release, upregulates pro‐regenerative LAMB2, downregulates inhibitory CSPG, and promotes axonal regeneration.
Shiyu Fu   +8 more
wiley   +1 more source

Brain topology alteration in Alzheimer's disease brain networks: A multi-center study. [PDF]

open access: yesNeuroimage Clin
Ma L   +15 more
europepmc   +1 more source

Solution‐Processed Thin‐Film Transistors With Tunable Temporal Dynamics for Neuromorphic Computing

open access: yesAdvanced Functional Materials, EarlyView.
Solution‐processed CNT and CNT/P3HT ion‐gated transistors exhibit materials‐defined synaptic timescales: fast CNT devices for high‐frequency spiking and slow hybrid devices for temporal integration. Embedding these dynamics into coupled reservoir‐computing and spiking neural network simulations reveals that a Hybrid‐Reservoir / CNT‐SNN architecture ...
Kevin Schnittker   +5 more
wiley   +1 more source

Subcortical Hubs of Brain Networks Sustaining Human Consciousness. [PDF]

open access: yesHum Brain Mapp
Cambareri MK   +4 more
europepmc   +1 more source

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

open access: yesAdvanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins   +9 more
wiley   +1 more source

Tomato Intake Improves Cognitive Performance and Modulates Functional Brain Networks in Healthy Adults: A Randomized Crossover Clinical Trial. [PDF]

open access: yesAntioxidants (Basel)
López-Solís R   +16 more
europepmc   +1 more source

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

open access: yesAdvanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones   +14 more
wiley   +1 more source

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