Results 161 to 170 of about 447,656 (309)
Advanced Functional Materials, EarlyView.A biomimetic hydrogel derived from neonatal spinal cord ECM (DNSCM) delivers LAMB2 protein and ISP peptide to remodel the inhibitory injury microenvironment. The system sustains drug release, upregulates pro‐regenerative LAMB2, downregulates inhibitory CSPG, and promotes axonal regeneration.
Shiyu Fu +8 more
wiley +1 more source
Solution‐Processed Thin‐Film Transistors With Tunable Temporal Dynamics for Neuromorphic Computing
Advanced Functional Materials, EarlyView.Solution‐processed CNT and CNT/P3HT ion‐gated transistors exhibit materials‐defined synaptic timescales: fast CNT devices for high‐frequency spiking and slow hybrid devices for temporal integration. Embedding these dynamics into coupled reservoir‐computing and spiking neural network simulations reveals that a Hybrid‐Reservoir / CNT‐SNN architecture ...
Kevin Schnittker +5 more
wiley +1 more source
Investigations into the use of human embryonal carcinoma stem cells as a model to study dopaminergic neurogenesis [PDF]
, 2009 Parkinson's disease in reality arises as a result of a complex series of events, however it is strongly linked to the loss of a specific cellular population of midbrain dopaminergic neurons making it a candidate for stem cell based research.
Bramwell, Thomas William
core
Association of Cord Ferritin Levels with Brain Stem Evoked Response Audiometry in Newborns. [PDF]
Indian J Otolaryngol Head Neck Surg, 2023 Sarin V +4 more
europepmc +1 more source
Advanced Functional Materials, EarlyView.We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins +9 more
wiley +1 more source
, 2011 PhDThe Polycomb group protein Bmi1 is a key transcriptional regulator of self renewal of embryonic and adult neural stem and progenitor cells (NSPC) and its over-expression has been shown to occur in several types of brain tumour.
Yadırgı, Gökhan
core
A Case of Brainstem Cavernous Angioma Presenting with Persistent Hiccups
Acta Medica Iranica, 2010 Intractable hiccup most be considered as a symptom of underlying serious pathologies. We report a case of medulla oblongata cavernous angima presented with persistant hiccup and without any improvement during routine nonpharmacologic and pharmacologic ...
Mohammad Ali Arami
doaj
In reply: Withholding therapeutic interventions in brain(stem) death: is it a self-fulfilling prophecy? [PDF]
Can J Anaesth, 2022 Walter U, Cantré D, Zitzmann A.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley +1 more source
Astrocytes as Neural Stem Cells in the Adult Brain
, 2012 In the adult mammalian brain, bona fide neural stem cells were discovered in the subventricular zone (SVZ), the largest neurogenic niche lining the striatal wall of the lateral ventricles of the brain. In this region resides a subpopulation of astrocytes
Gonzalez-Perez, O. +1 more
core +1 more source