Results 21 to 30 of about 77 (53)

Modelo para portal corporativo para a gestão do conhecimento [PDF]

, 2011
Dissertação de Mestrado em Comércio Electrónico e Internet apresentada à Universidade AbertaA presente dissertação centra-se no domínio da gestão do conhecimento.
Santos, Sandra Cristina Ferraz dos
core  

Assessing the Safety Margin for Micromotion‐Induced Strain at Electrode–Tissue Interface: A Finite Element Analysis via COMSOL

Advanced Materials Interfaces, Volume 12, Issue 9, May 5, 2025.
Brain movement significantly impacts the biocompatibility of neural probes due to continuous strain on neural tissue. This study examines strain profiles across various brain models and movement types, challenging the 5% damage threshold at the electrode–tissue interface.
Ali Sharbatian, Akhilesh Kamtikar, Danesh Ashouri Vajari, Thomas Stieglitz   +3 more
wiley   +1 more source

Assessing the Safety Margin for Micromotion‐Induced Strain at Electrode–Tissue Interface: A Finite Element Analysis via COMSOL (Adv. Mater. Interfaces 9/2025)

Advanced Materials Interfaces, Volume 12, Issue 9, May 5, 2025.
Neural Device Development In article 2401001, Danesh Ashouri Vajari, Thomas Stieglitz, and co‐workers investigate the impact of brain movement on the biocompatibility of neural probes by simulating strain profiles at the electrode‐tissue interface under various displacements.
Ali Sharbatian, Akhilesh Kamtikar, Danesh Ashouri Vajari, Thomas Stieglitz   +3 more
wiley   +1 more source

Dysregulation of Myelination in Focal Cortical Dysplasia Type II of the Human Frontal Lobe

Glia, Volume 73, Issue 5, Page 928-947, May 2025.
Main Points FCD IIa shows a normal radial myelin fiber pattern, thinner myelin sheaths and reduced myelin synthesis. FCD IIb has disorganized myelinated fibers, thicker myelin sheaths, more oligodendrocytes, and an increased transcription rate of myelin genes.
Catharina Donkels, Ute Häussler, Susanne Huber, Nina Tiesmeyer, Theo Demerath, Christian Scheiwe, Mukesch J. Shah, Marcel Heers, Horst Urbach, Andreas Schulze‐Bonhage, Marco Prinz, Andreas Vlachos, Jürgen Beck, Julia M. Nakagawa, Carola A. Haas   +14 more
wiley   +1 more source

Area Selective Atomic Layer Deposition for the Use on Active Implants: An Overview of Available Process Technology

Advanced Healthcare Materials, Volume 14, Issue 4, February 7, 2025.
Area‐selective atomic layer deposition (ASD) offers wide‐ranging potential for the use on active implants. As the active implants consist of heterogeneous materials, this provides an excellent basis for the application of ASD. In this review, processes for the application on active implants and possible application scenarios are highlighted.
Nicolai Simon, Thomas Stieglitz, Volker Bucher   +2 more
wiley   +1 more source

Chronic in vivo sequelae of repetitive acute mfb‐DBS on accumbal dopamine and midbrain neuronal activity

Journal of Neurochemistry, Volume 169, Issue 1, January 2025.
The study sheds light on how medial forebrain bundle Deep Brain Stimulation (mfb‐DBS) triggers neural activity and dopamine release in free and behaving animals. Over 8 weeks, 130 Hz mfb‐DBS significantly boosted accumbal dopaminergic activity, increasing phasic and tonic responses.
Lidia Miguel Telega, Danesh Ashouri Vajari, Chockalingam Ramanathan, Volker A. Coenen, Máté D. Döbrössy   +4 more
wiley   +1 more source

Process‐Informed Neural Networks: A Hybrid Modelling Approach to Improve Predictive Performance and Inference of Neural Networks in Ecology and Beyond

Ecology Letters, Volume 27, Issue 11, November 2024.
In this work, we combine process‐based models and neural networks into process‐informed neural networks (PINNs), which incorporate the process knowledge directly into the neural network structure. In a systematic evaluation of spatial and temporal prediction tasks for C‐fluxes in temperate forests, we show the ability of five different types of PINNs ...
Marieke Wesselkamp, Niklas Moser, Maria Kalweit, Joschka Boedecker, Carsten F. Dormann   +4 more
wiley   +1 more source

Recording Quality Is Systematically Related to Electrode Impedance

Advanced Healthcare Materials, Volume 13, Issue 24, September 25, 2024.
Electrode coatings bringing the impedance of small electrodes closer to the impedance of large ones and allow increased spike selectively without sacrificing the SNR and unit‐yield. This study shows that in chronic recordings, signal quality and unit yield are negatively correlated with electrode impedance.
Christopher M. Lewis, Christian Boehler, Rickard Liljemalm, Pascal Fries, Thomas Stieglitz, Maria Asplund   +5 more
wiley   +1 more source

Low rate hippocampal delay period activity encodes behavioral experience

Hippocampus, Volume 34, Issue 8, Page 422-437, August 2024.
Abstract Remembering what just happened is a crucial prerequisite to form long‐term memories but also for establishing and maintaining working memory. So far there is no general agreement about cortical mechanisms that support short‐term memory.
Markos Athanasiadis, Stefano Masserini, Li Yuan, Dustin Fetterhoff, Jill K. Leutgeb, Stefan Leutgeb, Christian Leibold   +6 more
wiley   +1 more source

Bioelectronic Direct Current Stimulation at the Transition Between Reversible and Irreversible Charge Transfer

Advanced Science, Volume 11, Issue 27, July 17, 2024.
Direct current electric fields (dcEFs) naturally occur in wound healing or cancer metastasis. The stimulus to generate dcEFs may release toxic stimulation by‐products. The release can be delayed by increasing the capacitance of the stimulation electrode by coating the surface with conducting polymers.
Lukas Matter, Oliya S. Abdullaeva, Sebastian Shaner, José Leal, Maria Asplund   +4 more
wiley   +1 more source