Results 71 to 80 of about 30,312 (265)

A Nanobody‐LNP Platform for Targeting and Relicensing Dendritic Cells for Potent Cancer Immunotherapy

Advanced Science, EarlyView.
Plastin‐2 (PLS2) is identified as a dual‐function receptor on DCs that mediates both nanoparticle uptake and immunomodulation. A nanobody‐LNP platform is engineered to integrate antigen delivery with relicensing DCs. The therapeutic strategy elicits potent anti‐tumor T cell responses and leads to significant inhibition of established tumors in vivo ...
Shugang Qin, Zhiying Huang, Hai Huang, Yupei Zhang, Yuting Chen, Xi He, Zhenyi Niu, Zhongzheng Xiang, Chaoyu Zou, Xiangrong Song   +9 more
wiley   +1 more source

Comparison and Analysis of Electric Brake Management Scheme for Urban Rail Vehicles

机车电传动, 2019
The selection of electric brake management scheme for urban rail vehicles directly affects the service life of brake shoe of the brake system. Choosing reasonable electric brake management scheme can greatly reduce the wear of brake shoe of brake system ...
Rushi LI, Fuzheng REN, Junjun SONG
doaj  

Finite element analysis of advanced bicycle precision brake disk forming technology

MATEC Web of Conferences, 2015
In recent years, the bicycle has become an environmentally friendly transportation. The bicycle can be divided into mountain bicycle and highway bicycle. Safe driving is the prior consideration. The bicycle braking system can be divided into oil pressure
Chen Dyi-Cheng, Kang Jing-Hao, Lai Chia-Chun   +2 more
doaj   +1 more source

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

Advanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv, Yi Liu, Ning Xu, Xiao Zhang, Yaming Yang, Chengyao Li, Hanhai Mao, Mingyuan Liu, Xiaolei Liu   +8 more
wiley   +1 more source

Integrated Thermomechanical Analysis of Tires and Brakes for Vehicle Dynamics and Safety

Vehicles
The accurate prediction of tire and brake thermomechanical behavior is crucial for various applications in the automotive industry, including vehicle dynamics analysis, racing performance optimization, and driver assistance system development.
Andrea Stefanelli, Marco Aprea, Fabio Carbone, Fabio Romagnuolo, Pietro Caresia, Raffaele Suero   +5 more
doaj   +1 more source

Transcriptomic and Neuroimaging Decoding of Brain‐Immune Crosstalk in Thyroid Eye Disease

Advanced Science, EarlyView.
This study employed an imaging transcriptomics framework integrating resting‐state fMRI with Allen Human Brain Atlas transcriptomic data, coupled with peripheral blood RNA sequencing, to decode brain‐immune crosstalk in thyroid eye disease. Frontal, parietal, subcortical, and brainstem regions were identified as key neuroimmune‐ vulnerable regions ...
Haiyang Zhang, Yuting Liu, Shufan Jiang, Zilin Fang, Mengda Jiang, Xiaofeng Tao, Tianyi Zhu, Jipeng Li, Sijie Fang, Xuefei Song, Yinwei Li, Jing Sun, Chuanjun Tong, Zhengrun Gao, Huifang Zhou, Xianqun Fan   +15 more
wiley   +1 more source

Electroactive Metal–Organic Frameworks Enabling Unidirectional Electrochemical Capacitors and Logic Gates (MOF‐CAPode)

Angewandte Chemie, EarlyView.
MOF‐CAPodes are introduced by pairing various p‐MOFs with an n‐MOF as electrode materials in a battery‐like assembly. The devices achieve high figures of merit (RRI = 23.5; RRII = 94.4%) and perform excellently in prototypical logic gates (AND, OR) highlighting a new direction for ionological systems based on electroactive MOFs.
Tim Engelhardt, Leonid Shupletsov, Christin Gellrich, Cécilia Bauden, Przemyslaw Galek, Ahmed Bahrawy, Sonila Xhafa, Irena Senkovska, Julia Grothe, Stefan Kaskel   +9 more
wiley   +2 more sources

Comprehensive protection system of brake shoe of mine-used winch based on AT89C52

Gong-kuang zidonghua, 2013
In view of problem of bad reliability and poor real-time performance existed in brake shoe protection equipment of winch, a kind of comprehensive protection system of brake shoe of mine-used winch based on AT89C52 was designed, design of hardware and ...
ZUO Man-man, GENG Jin-fei, HUANG Cheng-hua, WANG Yong, LI Shuang-shuang   +4 more
doaj  

Brake System and its Control Strategy of Autonomous-rail Rapid Tram

Kongzhi Yu Xinxi Jishu, 2020
Based on the particularity of rail and road applications, this paper analyzed the special requirements of brake system for autonomous-rail rapid tram. Also, the top design goals and the overall scheme design were mentioned.
QIAN Hua, YU Jieren, LUO Xiaofeng, FU Jianchao, LIU Wenfeng, XIE Yongqing   +5 more
doaj  

A Soft Matrix Microenvironment Promotes Laterally Spreading Tumors via Oxidative Phosphorylation‐Dependent Cell Adhesion

Advanced Science, EarlyView.
Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong, Jingyi Lu, Haopeng Li, Jun Zhong, Xiaobei Luo, Yiyi Hu, Xianfei Wang, Pengfei Wang, Yanning Zhang, Zhenjiang Wang, Qiuhua Lai, Zhenyu Chen, Wenting Mi, Wang Tin San‐to, Weize Li, Shuping Tan, Qihong Cheng, Ruijia Li, Yida Nie, Side Liu, Bing Huang, Zelong Han   +21 more
wiley   +1 more source