Results 41 to 50 of about 1,249,681 (281)

Vibrational state dependence of ionic rotational branching ratios in resonance enhanced multiphoton ionization of CH [PDF]

, 1989
We show that rapid evolution of a Rydberg orbital with internuclear distance in a resonance enhanced multiphoton ionization (REMPI) process can have a profound influence on the production of molecular ions in alternative rotational states.
Lee, M.-T., McKoy, V., Rudolph, H., Stephens, J. A.   +3 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Study of a combined biological product with antibacterial and probiotic activity

Биопрепараты: Профилактика, диагностика, лечение, 2023
Scientific relevance. The issue of antimicrobial resistance has acquired global significance, urging the search for and use of alternative antibacterial agents to treat infectious diseases. In particular, this situation prompts wider use of biotechnology-
V. A. Neschislyaev, E. G. Shilova, A. M. Nikolaeva, E. V. Orlova   +3 more
doaj   +1 more source

Assessment of the role of age and light availability in leaf mortality in mango tree.[OS 6-1] [PDF]

, 2018
The branch autonomy principle states that the branch carbohydrate economy can be largely independent of the other branches of a tree. This may influence fruit growth and affect global crop yield.
Boudon, Frédéric, Fournier, Christian, Grechi, Isabelle, Lechaudel, Mathieu, Marquier, André, Normand, Frédéric, Soria, Christian   +6 more
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Modeling and Forecasting the Removal of Biogenic Elements from Agricultural Lands Depending on the Soil Agrophysical Properties

Инженерные технологии и системы
Introduction. Environmental pollution prevention, including prevention of water bodies, with nutrients (nitrogen and phosphorus) when they are removed from agricultural lands with possible runoff is a topical problem that requires a timely solution.
Nozim I. Jabborov, Anatoliy P. Savelyev, Aleksandr V. Dobrinov, Anton M. Zakharov, Ilya I. Zhuikov   +4 more
doaj   +1 more source

The role of branch architecture in assimilate production and partitioning: the example of Apple (Malus domestica)

Frontiers in Plant Science, 2014
Understanding the role of branch architecture in carbon production and allocation is essential to gain more insight into the complex process of assimilate partitioning in fruit trees.
Julienne eFanwoua, Emna eBairam, MICKAEL eDELAIRE, Gerhard eBuck-Sorlin   +3 more
doaj   +1 more source

Features of Middle-Lower Ordovician paleo-karst caves in western slope area, Tahe Oil Field, Tarim Basin

Shiyou shiyan dizhi, 2022
Seismic and drilling data were obtained to study the paleo-karst development conditions and cave developmental characteristics of the Middle-Lower Ordovician in the incised meandering canyon area on the western slope of Tahe Oilfield, Tarim Basin.
Changjian ZHANG, Yanping LÜ, Zhenzhe ZHANG   +2 more
doaj   +1 more source