Results 121 to 130 of about 38,416 (305)
Advanced Science, EarlyView.Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li +9 more
wiley +1 more source
The extremal position of a branching random walk on the general linear group [PDF]
, 2022 Ion Grama +2 more
openalex +1 more source
Advanced Science, EarlyView.GNL3 is a novel AR coregulator with dual coactivator and corepressor functions in prostate cancer (PCa). Our study uncovers a previously unrecognized mechanism by which the AR transcriptional complex integrates oncogenic signaling and immune suppression.
Cuiting Zhang +12 more
wiley +1 more source
Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis
Advanced Science, EarlyView.This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou +23 more
wiley +1 more source
Critical branching-annihilating random walk of two species [PDF]
, 2001 Géza Ódor
openalex +1 more source
Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis
Advanced Science, EarlyView.Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason +12 more
wiley +1 more source
Persistence of competing systems of branching random walks [PDF]
, 2011 Zakhar Kabluchko
openalex +1 more source
random walks in random environment and branching random walks
, 2009 This thesis deals with two models of random walks. The first model belongs to the family of random walks in random environment. In the case where the graph is a Galton-watson tree, we are interested in the asymptotic properties of the walk. When the walk is transient, we look at its speed.
openaire +1 more source
Advanced Science, EarlyView.TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang +17 more
wiley +1 more source
Harmonic Analysis of Branching Random Walks with Heavy Tails [PDF]
, 2022 A. I. Rytova
openalex +1 more source