Results 171 to 180 of about 1,983,959 (269)

Mathematical Modeling of Human Retinal Vascular Pattern Around the Foveal Avascular Zone. [PDF]

Transl Vis Sci Technol
Yoshimura K, Sugihara K, Maruko I, Iida T, Miura T.   +4 more
europepmc   +1 more source

Nano Proton Scavengers Modulate Endosomal pH to Inhibit Microglial Activation and Enhance Stroke Recovery

Advanced Science, EarlyView.
Amphiphilic sulfonated chitosan nanoparticles buffer endo/lysosomal acidity in microglia by limiting V‐ATPase membrane recruitment and restoring endosomal homeostasis. Following systemic administration, they accumulate in the ischemic hemisphere partly through association with infiltrating immune cells, suppress TLR3/IRF3 and TLR4/NF‐κB signaling ...
Xuanlin Wang, Yujing Shi, Zehua Gao, Jing Wang, Changsheng Liu   +4 more
wiley   +1 more source

HawkesRank: Event-driven centrality for real-time importance ranking. [PDF]

PNAS Nexus
Sornette D, Luo Y, Lera SC.
europepmc   +1 more source

NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment

Advanced Science, EarlyView.
The non‐invasive NICE framework, built on an ensemble stacking machine learning model, prioritizes embryos by analyzing cell‐free DNA from spent culture medium. By integrating multimodal signals, including genomic and epigenetic profiles, this automated approach standardizes morphological assessment without human bias, paving the way for more precise ...
Xueya Zhou, Shu Ding, Zhenyi Zhang, Qiaoling Shangguan, Jie Qiao, Peijie Zhou, Yidong Chen   +6 more
wiley   +1 more source

Imperfect Oriented Attachment of Gold Nanoparticles

Advanced Science, EarlyView.
The cover illustrates the imperfect oriented attachment of gold nanoparticles in liquid, as revealed by in situ liquid‐phase transmission electron microscopy. Triggered by the abrupt collapse of the interfacial hydration layer, two misoriented nanoparticles undergo a kinetically driven “jump‐to‐coalescence”.
Fangjie Meng, Peng Hu, Yongzhao Zhang, Gengshuo Zhang, Jiaqi Zhang, Ronghan Wei, Wen Wang, Shaobo Cheng   +7 more
wiley   +1 more source

Molecular descriptor driven QSPR modeling of Papp, TEER and Efflux Ratio from Caco-2 cells using machine learning for various phytochemicals. [PDF]

J Sci Food Agric
Kim JW, Cong R, Park JS, Park K, Kang K, Shim SM.   +5 more
europepmc   +1 more source

Atmospheric Water Harvesting Through Polymer Hydrogel Sorbents: Materials Chemistry, Design Strategies, and Applications

Advanced Science, EarlyView.
Polymer‐based hydrogels have emerged as promising materials for atmospheric water harvesting (AWH) due to their high water affinity, tunable network structure, and excellent moisture adsorption‐desorption performance. Functional hydrogel systems enable efficient water capture and controlled release under low‐energy conditions, offering a sustainable ...
Swagata Datta, Sushmit Sen, Nilanjan Dey, Amrita Chatterjee, Ananya Sadhu, Sudipta Sarkar, Pradip K. Maji   +6 more
wiley   +1 more source

A localisation phase transition for the catalytic branching random walk

We show the existence of a phase transition between a localisation and a non-localisation regime for a branching random walk with a catalyst at the origin.
Schapira, Bruno, Mailler, Cécile
core   +1 more source

Biophysical simulations of fMRI responses using realistic microvascular models: Insights into distinct hemodynamics in humans and mice. [PDF]

Imaging Neurosci (Camb)
Hartung G, Berman AJL, Sakadžić S, Linninger A, Boas DA, Polimeni JR.   +5 more
europepmc   +1 more source

A Unified Hierarchical Multiscale Fusion Framework for Drug–Target Affinity Prediction: From Benchmark Performance to Nanomolar Inhibitor Discovery

Advanced Science, EarlyView.
A multimodal fusion framework integrating sequence, atomic, and fragment representations captures drug–target interactions across multiple scales. The model delivers strong predictive performance and enables efficient virtual screening. Applied to hematopoietic progenitor kinase 1 (HPK1), it identifies structurally diverse inhibitors with nanomolar ...
Shuo Liu, Xiang Zhang, Haixia Feng, Yuquan Li, Xiaoqing Gong, Yong Liang, Xiaojun Yao, Huanxiang Liu   +7 more
wiley   +1 more source