Results 231 to 240 of about 38,313 (309)

A biomimetic branching signal-passing tile assembly model with dynamic growth and disassembly. [PDF]

J R Soc Interface
Fu D, Reif J.
europepmc   +1 more source

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao, Haiyun Chen, Yanan Zhu, Zhiping Xia, Hangyuan He, Yutang Liu, Tianshu Yang, Hui Wang, Ying Ao   +8 more
wiley   +1 more source

Forelimb reduction and digit loss were evolutionarily decoupled in oviraptorosaurian theropod dinosaurs. [PDF]

R Soc Open Sci
Mead A, Funston G, Brusatte S.
europepmc   +1 more source

Amelioration of Post‐Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System

Advanced Science, EarlyView.
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin, Zeyu Yang, Boyang Wei, Yu Wu, Longxiang Li, Jiaming Zhou, Xin Zhang, Fa Jin, Shixing Su, Yanchao Liu, Ran Li, Shenquan Guo, Xingwu Liu, Yu Cai, Hong Liu, Min Chen, Wenchao Liu, Chuanzhi Duan, Xifeng Li   +18 more
wiley   +1 more source

Neural xenografts contribute to long-term recovery in stroke via molecular graft-host crosstalk. [PDF]

Nat Commun
Weber RZ, Achón Buil B, Rentsch NH, Perron P, Halliday S, Bosworth A, Zhang M, Kisler K, Bodenmann C, Zürcher KJ, Uhr D, Meier D, Peter SL, Generali M, Lin S, Rüegg MA, Nitsch RM, Tackenberg C, Rust R.   +18 more
europepmc   +1 more source

SAGE: Spatially Aware Gene Selection and Dual‐View Embedding Fusion for Domain Identification in Spatial Transcriptomics

Advanced Science, EarlyView.
SAGE is a unified framework for spatial domain identification in spatial transcriptomics that jointly models tissue architecture and gene programs. Topic‐driven gene selection (NMF plus classifier‐based scoring) highlights spatially informative genes, while dual‐view graph embedding fuses local expression and non‐local functional relations.
Yi He, Yunpei Xu, Liqing Ding, Hong‐Dong Li, Yaohang Li, Shaokai Wang   +5 more
wiley   +1 more source

Highly Branched Sulfated Glycopolymers as Mucin Mimetics. [PDF]

J Am Chem Soc
Feldhof MI, Schlatterer R, Strahl F, Garthe J, Prévost S, Schmidt S, Karg M, Balzer BN, Hartmann L.   +8 more
europepmc   +1 more source

Scaling limit of the path leading to the leftmost particle in a branching random walk

, 2014
X Chen, X Chen
openalex   +2 more sources

Enhanced Bandgap Flexibility in Perovskite‐Silicon Tandem Solar Cells via Three‐Terminal Architecture

Advanced Science, EarlyView.
Three‐terminal (3T) perovskite/silicon tandem solar cells overcome the current‐matching constraints of 2T designs. Using an IBC POLO silicon bottom cell, we demonstrate a 30.1% PCE, with performance largely decoupled from perovskite bandgap and enhanced resilience under realistic, time‐dependent solar spectra.
Mohammad Gholipoor, Michael Rienaecker, Xuzheng Liu, Seyedamir Orooji, Lingyi Fang, Paul Fassl, Renjun Guo, Uli Lemmer, Robby Peibst, Ulrich Wilhelm Paetzold   +9 more
wiley   +1 more source

Cell-Based Computational Models of Organoids: A Systematic Review. [PDF]

Cells
Neagu M, Robu A, Arjoca S, Neagu A.
europepmc   +1 more source