Results 241 to 250 of about 38,313 (309)

A Subset of Pro‐inflammatory CXCL10+ LILRB2+ Macrophages Derives From Recipient Monocytes and Drives Renal Allograft Rejection

open access: yesAdvanced Science, EarlyView.
This study uncovers a recipient‐derived monocyte‐to‐macrophage trajectory that drives inflammation during kidney transplant rejection. Using over 150 000 single‐cell profiles and more than 850 biopsies, the authors identify CXCL10+ macrophages as key predictors of graft loss.
Alexis Varin   +16 more
wiley   +1 more source

How Long are the Arms in DBM? [PDF]

open access: yesCommun Math Phys
Losev I, Smirnov S.
europepmc   +1 more source

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

open access: yesAdvanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang   +12 more
wiley   +1 more source

NEURD offers automated proofreading and feature extraction for connectomics. [PDF]

open access: yesNature
Celii B   +57 more
europepmc   +1 more source

Tunable Sound Absorption via Evanescent‐Wave Coupling in Asymmetric Bilayer Metasurfaces

open access: yesAdvanced Science, EarlyView.
Tunable sound absorption is realized through a bilayer metasurface system governed by evanescent‐wave coupling. This work demonstrates that such evanescent‐wave coupling provides a controllable scattering channel that destructively interferes with the specular reflection.
Pyung Sik Ma, Hyung Jin Lee
wiley   +1 more source

Systematic Engineering of Proteases in Saccharopolyspora Spinosa Reveals Synergistic Enhancement of Spinosad Biosynthesis via Substrate Flux Optimization

open access: yesAdvanced Science, EarlyView.
ARTP mutagenesis yielded Saccharopolyspora spinosa mutant D184 with improved extracellular nitrogen utilization. An integrated workflow of protease genetic manipulation, multi‐omics, and rational synergy design pinpointed a pepP‐clpP‐htpX synergistic triangular combination.
Duo Jin   +9 more
wiley   +1 more source

Local volume concentration, packing domains, and scaling properties of chromatin. [PDF]

open access: yesElife
Carignano MA   +8 more
europepmc   +1 more source

Versatile DNA Hydrogel‐Mediated Delivery of Ginsenoside‐Encapsulated Small Extracellular Vesicles to Boost Diabetic Wound Repair

open access: yesAdvanced Science, EarlyView.
This study presents a DNA hydrogel‐mediated delivery system, in which ginsenoside (GS) molecules are incorporated into small extracellular vesicles (sEV) secreted by mesenchymal stem cells (MSCs) and the formed complexes are then anchored in DNA hydrogels via aptamer‐CD63 affinity as “GS/sEV@DNAgels”, to improve diabetic wound repair.
Jianming Xing   +14 more
wiley   +1 more source

Machine learning approach to gait analysis for Parkinson's disease detection and severity classification. [PDF]

open access: yesFront Robot AI
Mittal R   +7 more
europepmc   +1 more source

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