Results 41 to 50 of about 47,011 (248)

Real‐world use of Cenobamate in pediatric drug‐resistant epilepsy: A European multicenter retrospective study

open access: yesEpilepsia Open, EarlyView.
Abstract Pediatric drug‐resistant epilepsy (DRE) remains a significant clinical challenge, with few effective pharmacological options. This European multicenter retrospective study assessed the real‐world efficacy, tolerability, and retention of off‐label cenobamate (CNB) in 108 children and adolescents with DRE (median age: 13.83 years, range 3.9–19.8)
Konstantin L. Makridis   +14 more
wiley   +1 more source

Post-Socialist Urban Futures: Decision-Making Dynamics behind Large-Scale Urban Waterfront Development in Belgrade and Bratislava

open access: yesUrban Planning, 2019
This article discusses the implementation of two large-scale urban waterfront projects that are currently under construction in the Central and Eastern European (CEE) capital cities of Belgrade and Bratislava.
Branislav Machala, Jorn Koelemaij
doaj   +1 more source

From Survival to Growth: Digital Strategies for Micro and Small Enterprises

open access: yesStrategic Change, EarlyView.
ABSTRACT This study investigates the critical factors influencing Digital Transformation (DT) in micro, small, and medium enterprises (MSMEs) within the post‐pandemic context. Data were collected through an online survey of 341 respondents and analyzed using Partial Least Square Structural Equation Modeling (PLS‐SEM).
Andrej Přívara   +4 more
wiley   +1 more source

Do Concentrated Owners Pay Less? French Evidence on Tax Avoidance and Female Directors

open access: yesStrategic Change, EarlyView.
ABSTRACT This study examines whether concentrated voting control increases corporate tax avoidance in French listed firms and whether board gender diversity and audit committee independence constrain that relationship. Using 3388 firm‐year observations from 242 CAC All Shares firms from 2009 to 2022, the analysis combines hand‐collected voting rights ...
Habiba Laadhari   +4 more
wiley   +1 more source

In‐frame variants in TP53 gene identified in adult leukemia samples are predominantly deleterious: a study of the TP53 Network of Education and Research Initiative on CLL

open access: yesThe Journal of Pathology, EarlyView.
Abstract The prognostic and predictive impact of TP53 variants in leukemia led to their inclusion in diagnostic and treatment guidelines, increasing the demand for rapid, reliable laboratory analysis, interpretation, and reporting. While most TP53 variants identified in tumor samples can be interpreted using data from large‐scale functional studies ...
Šárka Pavlová   +28 more
wiley   +1 more source

Insecure Bratislava: Between Initiation and Imitation (Ivan Horváth: Laco a Bratislava [Laco and Bratislava])

open access: yesSlovenska Literatura, 2021
The article focuses on the image of Bratislava during the first Czechoslovak Republic as presented in Ivan Horváth’s novella Laco a Bratislava. The city is viewed through the prism of the protagonist’s revaluation of his ideals and as a site of the possibilities it provides on the personal and social level.
openaire   +1 more source

UNPACKING THE SUSTAINABILITY FIX: Governance Mechanisms in Urban Redevelopment Across Central and Eastern Europe

open access: yesInternational Journal of Urban and Regional Research, EarlyView.
Abstract This article examines how sustainability is mobilized as a governance strategy in large‐scale urban redevelopment. Focusing on the RIVUS Mall project in Cluj‐Napoca, alongside comparative cases from Bratislava and Gdańsk, it traces how environmental objectives are translated into institutional practices, planning rationales, and financial ...
MIHAI IACOB
wiley   +1 more source

Edges as ecological filters: Asymmetrical orientation‐specific arthropod activity across forest boundaries

open access: yesInsect Science, EarlyView.
Moderate retention forestry creates structurally sharp forest edges that act as ecological filters, shaping orientation‐specific activity of ground‐dwelling arthropods. Using drift‐fence pitfall traps, we show that activity aligned with ecotones is more frequent than activity across forest–clearcut boundaries, particularly among detritivores.
Dominik Stočes   +3 more
wiley   +1 more source

Improving the Understanding of Late Effects of Testicular Cancer in Adolescent and Young Adult Survivors: TRANSCEND‐XR

open access: yesAndrology, EarlyView.
ABSTRACT Background Testicular cancer (TC) is the most common malignancy amongst adolescents and young adults (AYAs) aged 15–39 years assigned male at birth. Survivors often experience late effects of treatment and report unmet supportive care needs.
Mohamad M. Saab   +30 more
wiley   +1 more source

sGC stimulator BAY 41‐8543 improves survival and ventricular function in a rat model of doxorubicin‐induced cardiomyopathy with nephrotic syndrome

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Anthracyclines such as doxorubicin (DOXO) remain a cornerstone of cancer therapy but are associated with a high risk of cardiotoxicity and subsequent heart failure (HF). Impairment of NO/soluble guanylyl cyclase (sGC)/cGMP pathway has been reported in anthracycline‐induced cardiomyopathy.
Olga Gawrys   +14 more
wiley   +1 more source

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