Results 51 to 60 of about 4,908,628 (384)
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Issues and Challenges in Open and Distance e-Learning: Perspectives from the Philippines
International Review of Research in Open and Distributed Learning, 2016 Rapid advances in information and communications technology in the digital age have brought about significant changes in the practice of distance education (DE) worldwide.
Patricia Brazil Arinto
doaj +1 more source
IMAGENS DO FEMININO NO BANQUETE DE PLATÃO: SÓCRATES E A FLAUTISTA
Kínesis, 2021 O presente trabalho tem como objetivo central a análise e discussão da questão do feminino nos cinco primeiros discursos que compõem um dos mais célebres diálogos platônicos, O Banquete.
Vicente Thiago Freire Brazil
doaj +1 more source
Geographic Expansion of Sporotrichosis, Brazil
Emerging Infectious Diseases, 2020 Brazil has experienced geographic expansion of zoonotic sporotrichosis. Social problems in the country contribute substantially to the expansion. A comprehensive sporotrichosis control program is beyond the sphere of public health.
I. D. Gremião +4 more
semanticscholar +1 more source
Genetic analysis of members of the species Oropouche virus and identification of a novel M segment sequence [PDF]
, 2015 Oropouche virus (OROV) is a public health threat in South America, and in particular Northern Brazil, causing frequent outbreaks of febrile illness.
Azevedo, Raimunda S.S. +8 more
core +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities
Annals of Clinical and Translational Neurology, EarlyView.Chronic pain affected 66.2% of 10,631 individuals with Parkinson's disease, with higher prevalence and severity in females. Pain most often involved the buttocks, lower back, neck, and knees, and was linked to depression, sleep disorders, and osteoarthritis.
Natalia S. Ogonowski +13 more
wiley +1 more source
Revista de Estudios Sociales, 2023 The contemporary Brazilian context offers a growing artistic and cultural production, generated by LGBTQIA+ subjects, which disputes narratives and sensitivity, and suggests new ways of being in the social world.
Laan Mendes de Barros +1 more
doaj +1 more source
Extreme Drought Events over Brazil from 2011 to 2019
Atmosphere, 2019 Drought-related disasters are among the natural disasters that are able to cause large economic and social losses. In recent years, droughts have affected different regions of Brazil, impacting water, food, and energy security. In this study, we used the
A. P. Cunha +13 more
semanticscholar +1 more source
Purkinje Cell Loss in Essential Tremor: Collective Data From 215 Brains Over a 21‐Year Period
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Essential tremor is a highly prevalent movement disorder. Pathological changes observed in essential tremor cerebella center around Purkinje cells and neighboring neuronal populations. Postmortem studies have variably, but not always, shown reduced Purkinje cell counts in essential tremor compared to controls.
Chloë A. Kerridge +4 more
wiley +1 more source