Results 81 to 90 of about 10,694 (214)
Kofler meint wahrscheinlich Alfeld, eine Stadt in Niedersachsen in der Nähe von Hildesheim.
openaire +1 more source
Twenty‐one compounds, including six dolabellanes diterpenes and one germacrene sesquiterpene that are new natural products, are reported from the brown algae Dictyota fasciola and Dictyota mediterranea collected from the Aegean Sea. Among them, some exhibit considerable antiviral activity against RNA (HCoV‐NL63, ZIKV) and DNA (HSV‐1) viruses.
Aikaterini Koutsaviti +10 more
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This review surveys the literature on light‐driven dearomative [2+2] cycloadditions of indoles, highlighting their power to access complex cyclobuta[b]indole frameworks. Advances in photocatalysis, sensitizer design, and reaction engineering enable selective and sustainable assembly of strained three‐dimensional architectures, expanding opportunities ...
Maria Chiara Cabua +4 more
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Lysine lactylation (Kla) serves as a metabolic–epigenetic switch governed by writer–eraser–reader regulatory systems, directly connecting the Warburg effect to diverse forms of tumour drug resistance. Intratumoural lactylation critically contributes to treatment failure in chemotherapy, targeted therapy and immunotherapy.
Juan Li +5 more
wiley +1 more source
Role of biofilms in antimicrobial resistance of the bacterial bovine respiratory disease complex
An increase in chronic, non-responsive bovine respiratory disease (BRD) infections in North American feedlot cattle is observed each fall, a time when cattle are administered multiple antimicrobial treatments for BRD.
Sara Andrés-Lasheras +3 more
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Natural Monoterpene Stylosin Induced Anticancer Effects on Human Colon Carcinoma Cells
Extraction of STL from Ferula ovina by TLC and structural confirmation by 1H NMR. Favorable pharmacokinetics. Reduced CRC cell viability in a time‐ and dose‐dependent manner. Induced apoptosis. Interacted with the active site of HGFR. ABSTRACT Colorectal carcinoma (CRC) ranks among the top five most common malignancies globally, characterized by a high
Sara Seyedshazileh +3 more
wiley +1 more source
ABSTRACT Quantitative modeling can guide drug development and regulatory decisions by providing insights into pharmacokinetics, pharmacodynamics, efficacy, and safety. Integrating models allows simulations that support dosing considerations. A simulation framework for belantamab mafodotin (B) in relapsed/refractory multiple myeloma was developed using ...
Fernando Carreño +8 more
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4', 5'-(1 6,17-epi-Androsteno-)pyrido [2', 3'-d]pyrimidine
Gerhard Bouchon +2 more
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IntroductionThis study assessed the risk of first treatment for bovine respiratory disease (BRD) given detection of nasopharyngeal bacteria (Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni) and corresponding likelihood of ...
Jennifer N. Abi Younes +4 more
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Why LA‐ICPMS Fission‐Track Age Data Are So Dispersed? A Pseudo‐EDM Solution
Abstract Fission track (FT) dating is a well‐established thermochronological technique widely used to reconstruct rocks' thermal histories. Over the past two decades, development of Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA‐ICPMS) has significantly advanced the application of FT dating by enabling rapid measurements of uranium ...
Yuntao Tian, Huixia Zhong
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