Results 101 to 110 of about 146,495 (254)
, 1959 breakage nThe breakage between the islands was neither wide enough nor deep enough for the vessel to pass through.DNE-cit (W.J.K.)Used IUsed IUsed ISource appears in DNE I as P 148 ...
core
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Investigation of the flotation behaviour of ball mill and IsaMill products [PDF]
, 2012 Includes bibliographical references.Valuable minerals that are used in various aspects of everyday life are buried in fossilised storages below the ground in the earth's crust.
Khonthu, Tsepang
core +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Mitigation of Edge Fracture in Tempered Glass During Abrasive Water Jet Cutting
Advances in Mechanical and Materials EngineeringWhen an 8 mm-thick glass hob plate is cut in a circular shape using high-pressure abrasive water jet cutting in two distinct sizes, it leads to issues such as breakage and burr formation along the edges.
Uğur Şimşir
doaj +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Ice block breakage within deforming ice rubble
, 2023 Funding Information: The authors are grateful for financial support from the Academy of Finland through the projects (309830) Ice Block Breakage: Experiments and Simulations (ICEBES), and (348586) WindySea: Modelling Engine to Design, Assess ...
Prasanna, Malith, Polojärvi, Arttu
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