Results 81 to 90 of about 987,593 (306)

Wnt/beta-catenin signaling controls development of the blood–brain barrier [PDF]

open access: yes, 2009
The blood–brain barrier (BBB) is confined to the endothelium of brain capillaries and is indispensable for fluid homeostasis and neuronal function. In this study, we show that endothelial Wnt/beta-catenin (beta-cat) signaling regulates induction and ...
Babbage, Jane   +14 more
core  

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Accumulation Behaviors of Different Particles and Effects on the Breakdown Properties of Mineral Oil under DC Voltage

open access: yesEnergies, 2019
Particles in transformer oil are harmful to the operation of transformers, which can lead to the occurrence of partial discharge and even breakdown.
Min Dan   +5 more
doaj   +1 more source

Single-Crystal N-polar GaN p-n Diodes by Plasma-Assisted Molecular Beam Epitaxy

open access: yes, 2017
N-polar GaN p-n diodes are realized on single-crystal N-polar GaN bulk wafers by plasma-assisted molecular beam epitaxy growth. The current-voltage characteristics show high-quality rectification and electroluminescence characteristics with a high on/off
Cho, YongJin   +4 more
core   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu   +11 more
wiley   +1 more source

Study on the influence of O2 on the breakdown voltage and self-recovery characteristics of c-C4F8/N2 mixture

open access: yesAIP Advances, 2018
The c-C4F8 gas is considered to have great potential as a gaseous medium for use in gas-insulated equipment due to its good insulation properties and its relatively low greenhouse gas potential (Global warming potential, GWP) relative to SF6.
Song Xiao   +6 more
doaj   +1 more source

Cracking the Code: Which Ocular Symptoms Predict Dry Eye Signs? Insights from a large international sicca registry

open access: yesArthritis Care &Research, Accepted Article.
Purpose The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögrens International Collaborative Clinical Alliance (SICCA) cohort. Methods Retrospective analysis examining 16 ocular symptoms (most graded 0‐4) and artificial tear (AT) use (graded 0‐3) as predictors of DED signs [abnormal ocular surface staining ...
Pragnya R Donthineni   +7 more
wiley   +1 more source

Experimental and Numerical Studies on a Centrifugal Pump with 2D-Curved Blades in Cavitating Condition [PDF]

open access: yes, 2001
In the presented study a special test-pump with 2D curvature blade geometry in cavitating and non-cavitating conditions was investigated using different experimental techniques and a 3D numerical model of cavitating flows.
Coutier-Delgosha, O.   +4 more
core  

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

The suitability of N2 to replace SF6 in a triggered spark-gap switch for pulsed power applications [PDF]

open access: yes, 2009
The high dielectric strength of sulphur hexafluoride (SF6) when compared with other gases, coupled with safety benefits such as non-flammability and non-toxicity, has seen the widespread use of SF6 for the insulation of switching components. However, SF6
Given, M.J.   +6 more
core  

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