Inversion breakpoints and the evolution of supergenes [PDF]
AbstractThe coexistence of discrete morphs that differ in multiple traits is common within natural populations of many taxa. Such morphs are often associated with chromosomal inversions, presumably because the recombination suppressing effects of inversions help maintain alternate adaptive combinations of alleles across the multiple loci affecting ...
Villoutreix, Romain+5 more
openaire +5 more sources
Clustering of Translocation Breakpoints [PDF]
Translocation, a physical movement of genetic material from one chromosome to another, can result in the aberrant linkage of two cellular genes. This type of fusion may disrupt cellular function by producing novel, biologically active fused genes, or by triggering the activation of normally quiescent growth-associated genes.
Segal, Mark R, Wiemels, Joseph L
openaire +4 more sources
Breakpoint medians and breakpoint phylogenies: A fixed-parameter approach [PDF]
Abstract With breakpoint distance, the genome rearrangement field delivered one of the currently most popular measures in phylogenetic studies for related species. Here, Breakpoint Median, which is NP-complete already for three given species (whose genomes are represented as signed orderings), is the core basic problem. For the important
Jens Gramm, Rolf Niedermeier
openaire +3 more sources
Statistics of Solar Wind Electron Breakpoint Energies Using Machine Learning Techniques [PDF]
Solar wind electron velocity distributions at 1 au consist of a thermal "core" population and two suprathermal populations: "halo" and "strahl". The core and halo are quasi-isotropic, whereas the strahl typically travels radially outwards along the ...
Bakrania, Mayur R.+6 more
core +2 more sources
Genome reorganization in different cancer types: detection of cancer specific breakpoint regions [PDF]
Background: Tumorigenesis is a multi-step process which is accompanied by substantial changes in genome organization. The development of these changes is not only a random process, but rather comprise specific DNA regions that are prone to the ...
Klein, Andreas+3 more
core +1 more source
Experimental observation of the longitudinal plasma excitation in intrinsic Josephson junctions [PDF]
We have investigated the current-voltage characteristics (IVCs) of intrinsic Josephson junctions (IJJs). Recently, it is predicted that the longitudinal plasma wave can be excited by the parametric resonance in IJJs.
A Irie+4 more
core +1 more source
Structure of the breakpoint region in CVC of the intrinsic Josephson junctions [PDF]
A fine structure of the breakpoint region in the current-voltage characteristics of the coupled intrinsic Josephson junctions in the layered superconductors is found.
Mahfouzi, F.+2 more
core +2 more sources
The elusive evidence for chromothripsis. [PDF]
The chromothripsis hypothesis suggests an extraordinary one-step catastrophic genomic event allowing a chromosome to 'shatter into many pieces' and reassemble into a functioning chromosome.
Bafna, Vineet+2 more
core +1 more source
A Concurrency-Agnostic Protocol for Multi-Paradigm Concurrent Debugging Tools [PDF]
Today's complex software systems combine high-level concurrency models. Each model is used to solve a specific set of problems. Unfortunately, debuggers support only the low-level notions of threads and shared memory, forcing developers to reason about ...
Marr, Stefan+4 more
core +3 more sources
The distribution of cycles in breakpoint graphs of signed permutations [PDF]
Breakpoint graphs are ubiquitous structures in the field of genome rearrangements. Their cycle decomposition has proved useful in computing and bounding many measures of (dis)similarity between genomes, and studying the distribution of those cycles is ...
Anthony Labarre+23 more
core +6 more sources