Results 91 to 100 of about 127,256 (329)

Algorithms for the continuous nonlinear resource allocation problem---new implementations and numerical studies

, 2015
Patriksson (2008) provided a then up-to-date survey on the continuous,separable, differentiable and convex resource allocation problem with a single resource constraint.
Patriksson, Michael, Strömberg, Christoffer   +1 more
core   +1 more source

Long‐Read Whole‐Genome Sequencing Uncovers a Deletion Upstream to HOXD13 Causing Synpolydactyly

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Synpolydactyly (SPD) is a heterogeneous distal‐limb malformation syndrome, characterized by webbing and duplication of adjacent digits. SPD1, the most common type, is attributed to disease‐causing variants in HOXD13, a transcription factor in the HOXD cluster that is essential for limb development. Here, we present a challenging exome‐negative
Jonathan Rips, Rivka Birnbaum, Chaim Jalas, Ayala Frumkin, Shamir Zenvirt, Julia Rachanaev, Avraham Shaag, Tamar Harel, Orly Elpeleg, Hagar Mor‐Shaked   +9 more
wiley   +1 more source

Methods for detecting heat stress in hutch-housed dairy calves in a continental climate

Journal of Dairy Science, 2023
: Dairy calves exposed to solar radiation, elevated ambient temperature, and humidity are at risk of impaired welfare and productivity. Initial detection of thermal discomfort requires determination of optimal heat stress indicators and thresholds.
B. Dado-Senn, V. Ouellet, V. Lantigua, J. Van Os, J. Laporta   +4 more
doaj  

Resolving the Diagnostic Odyssey in Inherited Retinal Dystrophies Through Long‐Read Genome Sequencing

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Inherited retinal dystrophies (IRDs) inherited are visually disabling monogenic diseases with remarkable genetic and phenotypic heterogeneity. Mutations in more than 300 different genes have been identified as disease‐causing. The genetic diagnosis of IRDs has significantly advanced with the integration of Next Generation Sequencing (NGS ...
Gerardo E. Fabian‐Morales, Vianey Ordoñez‐Labastida, William J. Rowell, Christine Lambert, Cairbre Fanslow, Alexander Robertson, Juan C. Zenteno   +6 more
wiley   +1 more source

Reassessment of the evolution of wheat chromosomes 4A, 5A, and 7B. [PDF]

, 2018
Key messageComparison of genome sequences of wild emmer wheat and Aegilops tauschii suggests a novel scenario of the evolution of rearranged wheat chromosomes 4A, 5A, and 7B.
Deal, Karin R, Devos, Katrien M, Distelfeld, Assaf, Dvorak, Jan, Gill, Bikram S, Gu, Yong Q, Jorgensen, Chad M, Luo, Ming-Cheng, McGuire, Patrick E, Qi, Peng, Wang, Le, Zhu, Tingting   +11 more
core  

Unraveling the Genomic Architecture of Supernumerary (Iso‐)Dicentric Chromosomes in Dup15q Syndrome: Insight From a Systematic Literature‐Based Study

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Chromosomal aberrations, particularly copy‐number variations (CNVs), are prevalent in neurodevelopmental disorders (NDD) and significantly contribute to their pathogenesis. Copy‐number gains (CN gains) in 15q11‐q13, primarily consisting of a pseudo (iso‐)dicentric chromosome 15 [(i)dic(15)] or an interstitial duplication, are among the most ...
Sebastian Burkart, Markus Ries, Verena Romero, Karin Burau, Christian P. Schaaf, Maja Hempel   +5 more
wiley   +1 more source

Optimalisasi Sifat Reologi Hidrogel Kitosan-Hialuronat yang Ditaut-Silang dengan Glutaraldehida

Alchemy, 2019
Kitosan membentuk hidrogel polikationik dengan penambahan glutaraldehida sebagai penaut-silang. Penambahan hialuronat yang bersifat polianionik diharapkan akan meningkatkan sifat reologis hidrogel tersebut.
Pajri Samsi Nasution, Muhamad Alif Hamimdal, Gustini Syahbirin, Budi Arifin   +3 more
doaj   +1 more source

Limited Lifespan of Fragile Regions in Mammalian Evolution

, 2010
An important question in genome evolution is whether there exist fragile regions (rearrangement hotspots) where chromosomal rearrangements are happening over and over again. Although nearly all recent studies supported the existence of fragile regions in
A. Bergeron, A. Bhutkar, A. Kulemzina, A. Ruiz-Herrera, A. Ruiz-Herrera, A.E. Wind van der, C. Webber, D. Larkin, D. Misceo, D. San Mauro, D. Sankoff, D. Sankoff, D.M. Larkin, D.M. Larkin, E. Mlynarski, E. Mongin, E.E. Eichler, G. Fertin, H. Hinsch, H. Kikuta, H. Zhao, J. Ma, J. Ma, J.H. Nadeau, L. Armengol, L. Gordon, M. Caceres, M. Longo, M.A. Alekseyev, M.A. Alekseyev, M.A. Alekseyev, M.A. Alekseyev, M.R. Mehan, O. Lecompte, P. Pevzner, P.A. Pevzner, R. Koszul, S. Myers, S. Ohno, S. Yancopoulos, S. Zhao, W.J. Kent, W.J. Murphy, Y. Yue, Z. Jiang   +44 more
core   +3 more sources

Genomic Analysis of Trichotillomania

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Trichotillomania (TTM) is a psychiatric condition in which people feel an overwhelming urge to pull out their hair, resulting in noticeable hair loss and significant distress. Twin and family studies suggest that TTM is at least partly genetic, but no genome‐wide analyses have been completed.
Matthew W. Halvorsen, Melanie E. Garrett, Michael L. Cuccaro, Allison E. Ashley‐Koch, James J. Crowley   +4 more
wiley   +1 more source

Evaluation of resistance rates of enterobacterales to beta-lactam drugs and interpretation of their minimum inhibitory concentrations relative to clinical breakpoints [PDF]

Journal of Krishna Institute of Medical Sciences University
Background: Beta lactam group of antibiotics are one among the most widely used against enterobacterales. There has been an escalation of resistance among cephalosporins, and carbapenems in the recent days.
Uma BM, Neelesh Naik, Rama N.K
doaj