Results 101 to 110 of about 129,319 (328)

High-resolution mapping of reciprocal translocation breakpoints using long-read sequencing

open access: yesMethodsX, 2019
Long-read nanopore sequencing enables direct high-resolution breakpoint mapping on balanced carriers of reciprocal translocation. The mean sequencing depth on the translocated chromosomes to achieve accurate mapping of breakpoints ranged from 2.5-fold to
Judy F.C. Chow   +4 more
doaj   +1 more source

Long‐Term Stable Subdural Recordings Enabled by Fibrosis‐Resistant Hydrogel‐Integrated µECoG Arrays

open access: yesAdvanced Science, EarlyView.
An adhesive hydrogel‐integrated micro‐electrocorticography (aGel‐µECoG) array is developed to ensure stable neural recordings by minimizing neuroinflammation and fibrosis during implantation. The hydrogel serves as a biological and mechanical bridge, enabling bioadhesive, reversible, anti‐fibrotic integration with brain tissue.
Lin Chen   +13 more
wiley   +1 more source

Pericentric inversion in chromosome 1 and male infertility

open access: yesOpen Medicine, 2020
Pericentric inversion in chromosome 1 was thought to cause male infertility through spermatogenic impairment, regardless of the breakpoint position.
Li Ranwei   +5 more
doaj   +1 more source

novoBreak: local assembly for breakpoint detection in cancer genomes. [PDF]

open access: yes, 2017
We present novoBreak, a genome-wide local assembly algorithm that discovers somatic and germline structural variation breakpoints in whole-genome sequencing data.
Boutros, Paul   +10 more
core  

Price Transmission During Promotions: A Case Study of Spanish Milk Brands

open access: yesAgribusiness, EarlyView.
ABSTRACT Price promotion is the marketing tool typically used by retail brands to boost sales and gain market share. In this paper, we intend to investigate the price transmission mechanism among competitive brands in Spain when price reductions that are associated with price promotions take place.
Yasmine Bedoui   +2 more
wiley   +1 more source

River Flashiness in Great Britain: A Spatio-Temporal Analysis

open access: yesAtmosphere
Flashiness refers to the rapidity and frequency of fluctuations in river flow. It can provide insights into flooding, by capturing dramatic increases in river flow, as well as contaminant transport, relating to concentrations of diffuse pollution ...
Benjamin Olin, Lindsay Beevers
doaj   +1 more source

Partner independent fusion gene detection by multiplexed CRISPR-Cas9 enrichment and long read nanopore sequencing

open access: yesNature Communications, 2020
Fusion genes are a hallmarks of cancer, though breakpoint-position promiscuity restricts diagnostic detection. Here, the authors present FUDGE, a CRISPR-Cas9-based enrichment strategy for nanopore sequencing to identify target fusions irrespective of ...
Christina Stangl   +13 more
doaj   +1 more source

Joint segmentation of many aCGH profiles using fast group LARS

open access: yes, 2009
Array-Based Comparative Genomic Hybridization (aCGH) is a method used to search for genomic regions with copy numbers variations. For a given aCGH profile, one challenge is to accurately segment it into regions of constant copy number.
Bleakley, Kevin, Vert, Jean-Philippe
core   +1 more source

Pricing Dynamics in the US Hemp Market: A Vertical Price Transmission Analysis of the Hemp Value Chain

open access: yesAgribusiness, EarlyView.
ABSTRACT The US hemp market is a new and nascent industry that has been devoid of research for about half a century. This study examined the effects of exogenous shock on price at each phase of the value chain—Farm (hemp biomass), and its impact on prices at other phases of the value chain—Intermediary Processor (crude cannabidiol hemp) and Final ...
Solomon Odiase   +2 more
wiley   +1 more source

Climate-Related Default Probabilities

open access: yesRisks
Climate risk refers to the risks associated with climate change and has already started to impact various sectors of the economy. In this work, we focus on the impact of physical risk on the probability of default for a firm in the agribusiness sector ...
Augusto Blanc-Blocquel   +2 more
doaj   +1 more source

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