Results 101 to 110 of about 127,256 (329)

Evolutionary trends in antifungal resistance: a meta-analysis

Microbiology Spectrum
The present paper includes a meta-analysis of literature data on 318 species of fungi belonging to 34 orders in their response to 8 antifungal agents (amphotericin B, caspofungin, fluconazole, itraconazole, ketoconazole, posaconazole, terbinafine, and ...
Xueke Niu, Abdullah M. S. Al-Hatmi, Roxana G. Vitale, Michaela Lackner, Sarah A. Ahmed, Paul E. Verweij, Yingqian Kang, Sybren de Hoog   +7 more
doaj   +1 more source

Thermal stability of some aircraft turbine fuels derived from oil shale and coal [PDF]

Thermal stability breakpoint temperatures are shown for 32 jet fuels prepared from oil shale and coal syncrudes by various degrees of hydrogenation.
Reynolds, T. W.
core   +1 more source

Probability of pharmacokinetic/pharmacodynamic target attainment for different piperacillin/tazobactam dosing regimens in renally impaired patients in a non‐intensive care unit setting

British Journal of Clinical Pharmacology, EarlyView.
Aims To optimize antibiotic therapy for pathogens classified as susceptible, increased exposure (I), an increased exposure of piperacillin/tazobactam (PTZ) is required. However, dosing recommendations are currently only available for patients with normal renal function.
Emma Dohmann, Stefan Hagel, Max Kurlbaum, Paul Schellong, Oliver Scherf‐Clavel, Güzin Surat   +5 more
wiley   +1 more source

River Flashiness in Great Britain: A Spatio-Temporal Analysis

Atmosphere
Flashiness refers to the rapidity and frequency of fluctuations in river flow. It can provide insights into flooding, by capturing dramatic increases in river flow, as well as contaminant transport, relating to concentrations of diffuse pollution ...
Benjamin Olin, Lindsay Beevers
doaj   +1 more source

Pericentric inversion in chromosome 1 and male infertility

Open Medicine, 2020
Pericentric inversion in chromosome 1 was thought to cause male infertility through spermatogenic impairment, regardless of the breakpoint position.
Li Ranwei, Fan Haitao, Zhang Qiushuang, Yang Xiao, Zhan Peng, Feng Shuqiang   +5 more
doaj   +1 more source

A Running Time Improvement for Two Thresholds Two Divisors Algorithm [PDF]

, 2009
Chunking algorithms play an important role in data de-duplication systems. The Basic Sliding Window (BSW) algorithm is the first prototype of the content-based chunking algorithm which can handle most types of data. The Two Thresholds Two Divisors (TTTD)
Chang, BingChun
core   +1 more source

Cefuroxime axetil dosing regimens and probability of target attainment in adults and children

British Journal of Clinical Pharmacology, EarlyView.
Aims Cefuroxime axetil exists in several dosage forms for oral administration, and is indicated for treatment of respiratory, genitourinary, skin and soft tissue infections. Evolving patterns of bacterial susceptibility, expressed as increasing minimum inhibitory concentrations (MICs), warrant monitoring of antibiotic efficacy.
Sven C. van Dijkman, Praveen Kamble, Jerzy A. Kowalski, Oscar Della Pasqua   +3 more
wiley   +1 more source

Climate-Related Default Probabilities

Risks
Climate risk refers to the risks associated with climate change and has already started to impact various sectors of the economy. In this work, we focus on the impact of physical risk on the probability of default for a firm in the agribusiness sector ...
Augusto Blanc-Blocquel, Luis Ortiz-Gracia, Simona Sanfelici   +2 more
doaj   +1 more source

Partner independent fusion gene detection by multiplexed CRISPR-Cas9 enrichment and long read nanopore sequencing

Nature Communications, 2020
Fusion genes are a hallmarks of cancer, though breakpoint-position promiscuity restricts diagnostic detection. Here, the authors present FUDGE, a CRISPR-Cas9-based enrichment strategy for nanopore sequencing to identify target fusions irrespective of ...
Christina Stangl, Sam de Blank, Ivo Renkens, Liset Westera, Tamara Verbeek, Jose Espejo Valle-Inclan, Rocio Chamorro González, Anton G. Henssen, Markus J. van Roosmalen, Ronald W. Stam, Emile E. Voest, Wigard P. Kloosterman, Gijs van Haaften, Glen R. Monroe   +13 more
doaj   +1 more source

Functional regression with intensively measured longitudinal outcomes: a new lens through data partitioning

Canadian Journal of Statistics, EarlyView.
Abstract Modern longitudinal data from wearable devices consist of biological signals at high‐frequency time points. Distributed statistical methods have emerged as a powerful tool to overcome the computational burden of estimation and inference with large data, but methodology for distributed functional regression remains limited.
Cole Manschot, Emily C. Hector
wiley   +1 more source