Results 111 to 120 of about 127,476 (326)
Clinical Pharmacology &Therapeutics, EarlyView.Polymyxins are used against highly resistant Gram‐negative pathogens, and nephrotoxicity (acute kidney injury, AKI) is the major dose‐limiting adverse effect. We aimed to develop a well‐informed population pharmacokinetic/toxicodynamic (PK/TD) model using the largest polymyxin B‐treated critically ill patient population studied to inform polymyxin B ...
Patrick O. Hanafin +19 more
wiley +1 more source
Breath‐holding and its breakpoint [PDF]
Experimental Physiology, 2005 This article reviews the basic properties of breath‐holding in humans and the possible causes of the breath at breakpoint. The simplest objective measure of breath‐holding is its duration, but even this is highly variable. Breath‐holding is a voluntary act, but normal subjects appear unable to breath‐hold to unconsciousness.
openaire +3 more sources
Joint segmentation of many aCGH profiles using fast group LARS
, 2009 Array-Based Comparative Genomic Hybridization (aCGH) is a method used to search for genomic regions with copy numbers variations. For a given aCGH profile, one challenge is to accurately segment it into regions of constant copy number.
Bleakley, Kevin, Vert, Jean-Philippe
core +1 more source
Antimicrobial Susceptibility Testing of Pneumococci: Determination of Kirby-Bauer Breakpoints for Penicillin G, Erythromycin, Clindamycin, Tetracycline, Chloramphenicol, and Rifampin [PDF]
, 1979 Michael R. Jacobs +4 more
openalex +1 more source
Corporate Social Responsibility and Environmental Management, EarlyView.ABSTRACT This study investigates the relationship between board gender diversity (BGD) and environmental, social, and CSR controversies' performance and the moderating role of board size (BS) on their relationship. Using data from STOXX Europe 600 Index listed companies from 2007 to 2023 and employing a Generalized Method of Moments (GMM) model, the ...
Sofia Karagiannopoulou +3 more
wiley +1 more source
A complex double translocation involving four chromosomes and five breakpoints in a child with mild mental retardation. [PDF]
, 1983 D A Couzin, J L Watt, I.A. Auchterlonie
openalex +1 more source
ESC Heart Failure, EarlyView.Abstract Aims Most adults with stable heart failure are safe to exercise at a moderate intensity for 150 min/week. Regular participation in exercise may improve outcomes in adults with heart failure with preserved ejection fraction (HFpEF). Few adults with HFpEF initiate and sustain long‐term exercise. To promote exercise adherence in adults with HFpEF,
Windy W. Alonso +10 more
wiley +1 more source
Analysis of a single reference strain for determination of gentamicin regression line constants and inhibition zone diameter breakpoints in quality control of disk diffusion antibiotic susceptibility testing [PDF]
, 1982 G Kronvall
openalex +1 more source
Haematologica, 2009 The dic(9;20)(p11~13;q11) is a recurrent chromosomal abnormality in patients with acute lymphoblastic leukemia. Although it results in loss of material from 9p and 20q, the molecular targets on both chromosomes have not been fully elucidated.
Qian An +8 more
doaj +1 more source
Environmental and Molecular Mutagenesis, EarlyView.Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal +14 more
wiley +1 more source