Results 121 to 130 of about 127,256 (329)
The chromosome 14 breakpoint in neoplastic B cells with the t(11;14) translocation involves the immunoglobulin heavy chain locus. [PDF]
Jan Erikson+4 more
openalex +1 more source
Mechanisms of enhancer‐driven oncogene activation
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend+2 more
wiley +1 more source
The nerve growth factor receptor gene is at human chromosome region 17q12-17q22, distal to the chromosome 17 breakpoint in acute leukemias. [PDF]
Kay Huebner+9 more
openalex +1 more source
Epigenetic reprogramming in multiple myeloma—Challenges and opportunities
Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar+2 more
wiley +1 more source
What's New? Increases in diagnostic procedures involving fine‐needle aspiration (FNA) have fueled a rise in incidental thyroid nodule detection. This increase and the frequent need for repeat evaluation of FNA specimens place significant strain on healthcare systems.
Roos G. F. M. van der Ven+8 more
wiley +1 more source
Three patients with structurally abnormal X chromosomes, each with Xq13 breakpoints and a history of idiopathic acquired sideroblastic anemia [PDF]
GW Dewald, RV Pierre, RL Phyliky
openalex +1 more source
British Journal of Clinical Pharmacology, EarlyView.
Luka Bielen, Andro Vujević, Luka Csenar
wiley +1 more source
Abstract Liquid biopsy can revolutionize cancer patient management as repeated sampling allows real‐time monitoring of disease progression and response to treatment. The circulating transcriptome represents a rich source of potential cancer biomarkers, including coding and non‐coding RNAs.
Mengqian Li+7 more
wiley +1 more source
Philadelphia-positive chronic myeloid leukemia with a chromosome 22 breakpoint outside the breakpoint cluster region [published erratum appears in Blood 1988 Jan;71(1):272] [PDF]
Licia Selleri+8 more
openalex +1 more source
ABSTRACT We develop a theoretical framework that extends the Bernanke and Blinder model to incorporate imperfect substitution between internal and external finance of firms to study the operation of both the bank lending and the balance sheet channels of monetary transmission in the US.
Sophocles N. Brissimis+1 more
wiley +1 more source