Results 131 to 140 of about 129,319 (328)

Pathogenesis and potential therapeutic targets of trichorhinophalangeal syndrome; lessons obtained from animal studies

Developmental Dynamics, EarlyView.
Abstract Trichorhinophalangeal syndrome (TRPS) is a rare genetic disease inherited in an autosomal dominant manner. It occurs in 1 in 100,000 people globally and is caused by several types of mutations of the TRPS1 gene. Since the first human patient was reported in 1966, typical and atypical pathologies, disease courses, and treatment case ...
Naoya Saeki, Rinna Kanai, Sayuri Tatsuta, Shinichi Kawaguchi, Masatsune Itoh, Shinsuke Ohba, Makoto Abe   +6 more
wiley   +1 more source

Breakpoints of a Diachronic Experience

Critical Hermeneutics
Experience is investigated according to those breaking points where the unexpected surfaces and the surprise of the extraordinary and the alien breaks through. What happens is always in the postponement between pathos and response; this represents the fundamental agreement of a responsive phenomenology: it is never a quiet succession, but always ...
openaire   +3 more sources

Rainfall increases conformity and strength of species–area relationships

Ecography, EarlyView.
The positive relationship between species richness and area is regarded as one of the few laws in ecology. Therefore, deviations from predictable species–area scaling, evident as high residual variance in species–area curves, are often interpreted as anomalous behaviour.
Sebastian Steibl, Simon Steiger, Luís Valente, James C. Russell   +3 more
wiley   +1 more source

The chromosome 14 breakpoint in neoplastic B cells with the t(11;14) translocation involves the immunoglobulin heavy chain locus. [PDF]

, 1984
Jan Erikson, J Finan, Yuji Tsujimoto, Peter C. Nowell̀, Carlo M. Croce   +4 more
openalex   +1 more source

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

Linezolid breakpoints [PDF]

Clinical Microbiology and Infection, 2001
openaire   +2 more sources

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

A complex double translocation involving four chromosomes and five breakpoints in a child with mild mental retardation. [PDF]

, 1983
D A Couzin, J L Watt, I.A. Auchterlonie
openalex   +1 more source

Mealtime Physiological Responses in Individuals With Eating Disorders and Healthy Controls

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Mealtimes are highly distressing for individuals with eating disorders (ED), potentially reinforcing disordered eating and complicating recovery. Yet, physiological responses during meals remain understudied. This study explores autonomic nervous system responses during meals in individuals with ED and healthy controls (HC).
Emma De Schuyteneer, Robin Quagebeur, Femke de Gooijer, Annelies Goris, Neide Simões‐Capela, Alex van Kraaij, Elske Vrieze   +6 more
wiley   +1 more source

Transition Metal‐Based Materials for Electrochemical and Photoelectrochemical Carbon‐Free Nitrogen Cycling as H‐Carrier

Exploration, EarlyView.
This review summarizes the recent advanced progress of transition metal‐based catalysts used for electrochemical and photoelectrochemical ammonia synthesis and decomposition for hydrogen generation. The conclusion encapsulates the current challenges and prospects for the exploration of transition metal‐based materials in green ammonia conversion ...
Yuankai Li, Qian Lei, Won Tae Hong, Xinghui Liu, Chenyang Xue, Jung Kyu Kim   +5 more
wiley   +1 more source