Clonal rearrangement and expression of the T cell receptor beta gene and involvement of the breakpoint cluster region in blast crisis of CGL [PDF]
, 1986 Luen Chow Chan +4 more
openalex +1 more source
The Impact of Democratization and Globalization on Environmental Sustainability in Brazil
Geological Journal, EarlyView.Fossil fuel, economic globalisation, and economic growth drive environmental degradation while democratisation positively influences environmental quality. ABSTRACT Although Brazil still possesses significant ecological reserves, the surplus in its biocapacity has been rapidly declining in recent years.
Mustafa Naimoğlu +3 more
wiley +1 more source
806 TRANSLOCATION BREAKPOINT MAPPING OF 9;22 ALL AND 806 8;22 BURKITT'S LYMPHOMA REVEALS DIFFERING BREAK-POINTS WITHIN 22q11 [PDF]
, 1985 Linda A. Cannizzaro +4 more
openalex +1 more source
Mechanisms of enhancer‐driven oncogene activation
International Journal of Cancer, EarlyView.Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend +2 more
wiley +1 more source
Variable breakpoints on Ph1-chromosome [letter] [PDF]
, 1984 RS Verma, H Dosik
openalex +1 more source
Epigenetic reprogramming in multiple myeloma—Challenges and opportunities
International Journal of Cancer, EarlyView.Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar +2 more
wiley +1 more source
Does the breakpoint within the major breakpoint cluster region (M-bcr) influence the duration of the chronic phase in chronic myeloid leukemia? An analytical comparison of current literature [see comments] [PDF]
, 1991 Ken Mills, Peter Benn, GD Birnie
openalex +3 more sources
Breakpoint clustering in t(4;11)(q21;q23) acute leukemia [PDF]
, 1991 CS Chen +3 more
openalex +1 more source
International Journal of Cancer, EarlyView.What's New? Childhood cancer ranks among the leading causes of disease‐related deaths in children in high‐income countries. Established risk factors, however, account for only a small proportion of incident childhood cancers. In this report, the authors present the first long‐term assessment of temporal trends in childhood cancer incidence rates in ...
Friederike Erdmann +8 more
wiley +1 more source