Results 151 to 160 of about 168,262 (369)
The hidden regulators: Non‐coding RNAs in KMT2A‐rearranged acute lymphoblastic leukemia
Abstract Acute lymphoblastic leukemia (ALL) driven by KMT2A rearrangements (KMT2A‐r) is an aggressive hematologic malignancy with poor prognosis and a high incidence in infants. While KMT2A fusion proteins drive leukemogenesis through transcriptional dysregulation, recent discoveries have highlighted the pivotal role of non‐coding RNAs (ncRNAs) in ...
Maria Augusta Poersch +5 more
wiley +1 more source
Translocation breakpoints inFHIT and FRA3B in both homologs of chromosome 3 in an esophageal adenocarcinoma [PDF]
Jianming Fang +5 more
openalex +1 more source
ABSTRACT This paper studies herding and anti‐herding behaviour in three European stock markets before and during the Covid‐19 pandemic by employing both static and dynamic analysis. We examine four different questions related to herding behaviour: (i) Did herding behaviour increase during the pandemic? (ii) Does herding behaviour respond differently in
Dimitrios Asteriou +3 more
wiley +1 more source
5-HT1B receptor agonist enhances breakpoint for cocaine on a progressive ratio (PR) schedule during maintenance of self-administration in female rats but reduces breakpoint for sucrose [PDF]
Samantha N. Scott +6 more
openalex +1 more source
Abstract Background The triglyceride‐glucose body mass index (TyG‐BMI) is a novel indicator combining an insulin resistance proxy (TyG index) with adiposity. It remains unclear how TyG‐BMI relates to long‐term mortality risk in postmenopausal women, a group prone to metabolic changes after menopause.
Xiliang Wang +3 more
wiley +1 more source
Fusion transcripts and their genomic breakpoints in polyadenylated and ribosomal RNA–minus RNA sequencing data [PDF]
Youri Hoogstrate +27 more
openalex +1 more source
This study integrates two decades of surveillance with genomic and structural analyses to decipher how spike protein glycosylation haplotypes drive avian coronavirus evolution. We uncover how specific glycosylation patterns associate with receptor‐binding affinity, shape global transmission dynamics, and correlate with clinical outcomes.
Hao Zhang +21 more
wiley +1 more source
RNA‐based fusion panels using targeted next‐generation sequencing of formalin‐fixed paraffin‐embedded (FFPE) tumour tissue specimens have been used for a few years from patients with various tumour types to detect rearrangements/fusions. Using the bioinformatic approaches the data obtained from RNA sequencing (RNAseq) can also be used for small ...
Pranav Dorwal +14 more
wiley +1 more source
ABSTRACT Land degradation poses significant challenges to maintaining food–water–energy (FWE) security, particularly in rapidly urbanizing regions. The ecosystem services (ES) related to FWE are critical for sustainable regional development. Yet, rapid urbanization in the Beijing–Tianjin–Hebei region has altered land use and ecological patterns ...
Ke Yang, Qi Han, Dujuan Yang
wiley +1 more source

