Results 271 to 280 of about 127,256 (329)

Nursery Resource Use Dynamics in Great Hammerheads (<i>Sphyrna mokarran</i>) Across Ontogeny. [PDF]

Ecol Evol
Hlavin JF, Macdonald CC.
europepmc   +1 more source

A GLP‐1R/Y1 receptor/Y2 receptor triple agonist decreases fentanyl‐evoked dopamine release in the nucleus accumbens and attenuates fentanyl taking and seeking in rats

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Emerging literature indicates that simultaneously targeting glucagon‐like peptide‐1 receptors (GLP‐1Rs) and neuropeptide Y receptors (Y1/Y2) may represent a new pharmacotherapeutic approach to treating opioid use disorder (OUD).
Antonia Caffrey, Enzo Lavecchia, Kylie S. Chichura, Matthew R. Hayes, Robert P. Doyle, Heath D. Schmidt   +5 more
wiley   +1 more source

Cytogenomic characterization of karyotypes with additional autosomal material. [PDF]

Sci Rep
Rodrigues PS, Burssed B, Bellucco F, Rosolen DCB, Kim CA, Melaragno MI.   +5 more
europepmc   +1 more source

Genetic and Structural Variations in Czech Patients With Congenital Myopathies

Clinical Genetics, EarlyView.
We present 79 unrelated patients with genetically confirmed congenital myopathy (CM). A total of 113 mutant alleles carrying 97 different variants with a presumed pathogenic effect were identified. All but five variants were small scale. The mode of inheritance was autosomal dominant (AD) (44.3%), autosomal recessive (AR) (43.0%), and X‐linked (XL) (12.
Jana Zídková, Barbora Lauerová, Lívie Mensová, Tereza Kramářová, Johana Kopčilová, Kamila Réblová, Magdaléna Soukup Vodičková, Martina Hujňáková, Jana Haberlová, Marie Rohlenová, Radim Mazanec, Jana Šoukalová, Renata Gaillyová, Emílie Vyhnálková, Miroslava Balaščaková, Pavlína Danhofer, Lenka Juříková, Dagmar Grečmalová, Andrea Gřegořová, Pavlína Plevová, Martina Langová, Tomáš Honzík, Martin Magner, Martina Klincová, Pavla Solařová, Mária Šenkeříková, Lenka Fajkusová   +26 more
wiley   +1 more source

<i>TrexAB</i>, a novel tetracycline resistance determinant in <i>Streptococcus dysgalactiae</i>. [PDF]

Front Cell Infect Microbiol
Glambek M, Kjos M, Mårli MT, Salehian Z, Skrede S, Sivertsen A, Kittang BR, Oppegaard O.   +7 more
europepmc   +1 more source

Terrain descriptors for landscape synthesis, analysis and simulation

Computer Graphics Forum, EarlyView.
Abstract Synthetic landscape generation is an active research area within Computer Graphics. Algorithms for terrain synthesis and ecosystem simulations often rely on simple descriptors such as slope, light accessibility, and drainage area. Typically, the results are assessed from a perceptual standpoint, focusing primarily on visual plausibility. Other
O. Argudo, E. Guérin, H. Schott, E. Galin   +3 more
wiley   +1 more source

Homoharringtonine Promotes FTO Degradation to Suppress LILRB4‐Mediated Immune Evasion in Acute Monocytic Leukaemia

Cell Proliferation, EarlyView.
Homoharringtonine (HHT) suppresses immune evasion in acute monocytic leukaemia (AML‐M5) by attenuating the FTO/m6A/LILRB4 axis, thereby enhancing CD8+ T cell cytotoxicity. ABSTRACT Acute monocytic leukaemia, a subtype of acute myeloid leukaemia (AML), is a highly aggressive malignancy characterised by a poor prognosis, primarily due to the ability of ...
Fangfang Huang, Xiang Luo, Mengyu Zhang, Le Jin, Wenxin Sun, Peihan Chen, Xiuli Hong, Chenyu Xu, Meizhi Jiang, Die Hu, Bin Zhang, Shengwei Hu, Chuanjiang Yang, Rui Gao, Jinzhang Zeng, Quanyi Lu, Qiang Luo, Jun Wu, Siming Chen   +18 more
wiley   +1 more source

Serially Quantifying TERT Rearrangement Breakpoints in ctDNA Enables Minimal Residual Disease Monitoring in Patients with Neuroblastoma. [PDF]

Cancer Res Commun
Hollander JF, Szymansky A, Wünschel J, Astrahantseff K, Rosswog C, Thorwarth A, Thole-Kliesch TM, Chamorro González R, Hundsdörfer P, Hauptmann K, Schmelz K, Gürgen D, Rogasch JMM, Henssen AG, Fischer M, Schulte JH, Eckert C, Eggert A, Lodrini M, Deubzer HE.   +19 more
europepmc   +1 more source

Excess Alcohol‐Induced Hospitalisations and Deaths During the First Year of the COVID‐19 Pandemic in Australia

Drug and Alcohol Review, EarlyView.
ABSTRACT Introduction Since the onset of COVID‐19, alcohol‐related harm has increased in regions such as the United States and the United Kingdom. We examined whether alcohol‐related harm increased with the pandemic in Australia, and whether the impact varied across sex, age and type of alcohol diagnosis.
Wing See Yuen, Nicola Man, Michael Livingston, Agata Chrzanowska, William Gilmore, Louise Tierney, Lauren Moran, Amy Peacock   +7 more
wiley   +1 more source

Formation of multiple G-quadruplexes contributes toward BCR fragility associated with chronic myelogenous leukemia. [PDF]

Nucleic Acids Res
Sharma S, Thomas E, Dahal S, Das S, Kothari S, Roy U, Kumari N, Gopalakrishnan V, Raghavan SC.   +8 more
europepmc   +1 more source