Results 41 to 50 of about 168,262 (369)

The distribution of cycles in breakpoint graphs of signed permutations [PDF]

open access: yes, 2012
Breakpoint graphs are ubiquitous structures in the field of genome rearrangements. Their cycle decomposition has proved useful in computing and bounding many measures of (dis)similarity between genomes, and studying the distribution of those cycles is ...
Anthony Labarre   +23 more
core   +7 more sources

The elusive evidence for chromothripsis. [PDF]

open access: yes, 2014
The chromothripsis hypothesis suggests an extraordinary one-step catastrophic genomic event allowing a chromosome to 'shatter into many pieces' and reassemble into a functioning chromosome.
Bafna, Vineet   +2 more
core   +1 more source

Rationale for a Neisseria gonorrhoeae Susceptible Only Interpretive Breakpoint for Azithromycin.

open access: yesClinical Infectious Diseases, 2019
BACKGROUND Azithromycin (AZI) is recommended with Ceftriaxone (CRO) for treatment of uncomplicated gonococcal urethritis and cervicitis in the United States (US) and an AZI susceptibility breakpoint is needed.
E. Kersh   +8 more
semanticscholar   +1 more source

Sequencing and Characterisation of Rearrangements in Three S. pastorianus Strains Reveals the Presence of Chimeric Genes and Gives Evidence of Breakpoint Reuse [PDF]

open access: yesPLoS ONE, 2013
Gross chromosomal rearrangements have the potential to be evolutionarily advantageous to an adapting organism. The generation of a hybrid species increases opportunity for recombination by bringing together two homologous genomes. We sought to define the
Sarah K. Hewitt   +3 more
semanticscholar   +1 more source

Detecting Spatiotemporal Changes in Vegetation with the BFAST Model in the Qilian Mountain Region during 2000–2017

open access: yesRemote Sensing, 2019
The Qilian Mountain ecosystems play an irreplaceable role in maintaining ecological security in western China. Vegetation, as an important part of the ecosystem, has undergone considerable changes in recent decades in this area, but few studies have ...
Liying Geng   +3 more
doaj   +1 more source

Extinctions of aculeate pollinators in Britain and the role of large-scale agricultural changes [PDF]

open access: yes, 2014
Pollinators are fundamental to maintaining both biodiversity and agricultural productivity, but habitat destruction, loss of flower resources, and increased use of pesticides are causing declines in their abundance and diversity. Using historical records
Biesmeijer   +8 more
core   +1 more source

novoBreak: local assembly for breakpoint detection in cancer genomes

open access: yesNature Methods, 2016
We present novoBreak, a genome-wide local assembly algorithm that discovers somatic and germline structural variation breakpoints in whole-genome sequencing data.
Zechen Chong   +10 more
semanticscholar   +1 more source

Relative growth of the semi-terrestrial crab Pachygrapsus marmoratus: an information-theory approach

open access: yesScientia Marina, 2007
The patterns of allometric growth of the grapsid crab Pachygrapsus marmoratus were investigated with an information-theoretic approach. This approach is beneficial, more robust, and may reveal more information than the classical approaches (e.g ...
Nikos Prototapas   +3 more
doaj   +1 more source

Case report: Identification of a novel triplication of alpha-globin gene by the third-generation sequencing: pedigree analysis and genetic diagnosis

open access: yesHematology, 2023
Background Thalassemia, a common autosomal hereditary blood disorder worldwide, mainly contains α- and β-thalassemia. The α-globin gene triplicates allele is harmless for carriers, but aggravates the phenotype of β-thalassemia.
Yujiao Chen   +5 more
doaj   +1 more source

Lazy Probabilistic Model Checking without Determinisation [PDF]

open access: yes, 2015
The bottleneck in the quantitative analysis of Markov chains and Markov decision processes against specifications given in LTL or as some form of nondeterministic B\"uchi automata is the inclusion of a determinisation step of the automaton under ...
Hahn, Ernst Moritz   +4 more
core   +2 more sources

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