Results 51 to 60 of about 129,319 (328)

Cellular system information capacity change at higher frequencies due to propagation loss and system parameters [PDF]

open access: yes, 2012
In this paper, mathematical analysis supported by computer simulation is used to study cellular system information capacity change due to propagation loss and system parameters (such as path loss exponent, shadowing and antenna height) at microwave ...
Anang, K.A.   +4 more
core   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Study of charge-phase diagrams for coupled system of Josephson junctions

open access: yes, 2010
Dynamics of stacked intrinsic Josephson junctions (IJJ) in the high-Tc superconductors is theoretically investigated. We calculate the current-voltage characteristics (CVC) of IJJ and study the breakpoint region on the outermost branch of the CVC for the
Hamdipour, M., Shukrinov, Yu. M.
core   +1 more source

DNA topoisomerases participate in fragility of the oncogene RET [PDF]

open access: yes, 2013
Fragile site breakage was previously shown to result in rearrangement of the RET oncogene, resembling the rearrangements found in thyroid cancer. Common fragile sites are specific regions of the genome with a high susceptibility to DNA breakage under ...
A Ganguly   +86 more
core   +3 more sources

The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga   +8 more
wiley   +1 more source

Detecting Spatiotemporal Changes in Vegetation with the BFAST Model in the Qilian Mountain Region during 2000–2017

open access: yesRemote Sensing, 2019
The Qilian Mountain ecosystems play an irreplaceable role in maintaining ecological security in western China. Vegetation, as an important part of the ecosystem, has undergone considerable changes in recent decades in this area, but few studies have ...
Liying Geng   +3 more
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Relative growth of the semi-terrestrial crab Pachygrapsus marmoratus: an information-theory approach

open access: yesScientia Marina, 2007
The patterns of allometric growth of the grapsid crab Pachygrapsus marmoratus were investigated with an information-theoretic approach. This approach is beneficial, more robust, and may reveal more information than the classical approaches (e.g ...
Nikos Prototapas   +3 more
doaj   +1 more source

Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3

open access: yesFEBS Open Bio, EarlyView.
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno   +12 more
wiley   +1 more source

On the non-existence of an R-labeling

open access: yes, 2010
We present a family of Eulerian posets which does not have any R-labeling. The result uses a structure theorem for R-labelings of the butterfly poset.Comment: 6 pages, 1 figure.
A Björner   +14 more
core   +1 more source

Home - About - Disclaimer - Privacy