Results 51 to 60 of about 127,476 (326)
Methods for detecting heat stress in hutch-housed dairy calves in a continental climate
Journal of Dairy Science, 2023 : Dairy calves exposed to solar radiation, elevated ambient temperature, and humidity are at risk of impaired welfare and productivity. Initial detection of thermal discomfort requires determination of optimal heat stress indicators and thresholds.
B. Dado-Senn +4 more
doaj +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Study of charge-phase diagrams for coupled system of Josephson junctions
, 2010 Dynamics of stacked intrinsic Josephson junctions (IJJ) in the high-Tc superconductors is theoretically investigated. We calculate the current-voltage characteristics (CVC) of IJJ and study the breakpoint region on the outermost branch of the CVC for the
Hamdipour, M., Shukrinov, Yu. M.
core +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Remote Sensing, 2019 The Qilian Mountain ecosystems play an irreplaceable role in maintaining ecological security in western China. Vegetation, as an important part of the ecosystem, has undergone considerable changes in recent decades in this area, but few studies have ...
Liying Geng +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga +8 more
wiley +1 more source
On the non-existence of an R-labeling
, 2010 We present a family of Eulerian posets which does not have any R-labeling. The result uses a structure theorem for R-labelings of the butterfly poset.Comment: 6 pages, 1 figure.
A Björner +14 more
core +1 more source
DNA topoisomerases participate in fragility of the oncogene RET [PDF]
, 2013 Fragile site breakage was previously shown to result in rearrangement of the RET oncogene, resembling the rearrangements found in thyroid cancer. Common fragile sites are specific regions of the genome with a high susceptibility to DNA breakage under ...
A Ganguly +86 more
core +3 more sources
Relative growth of the semi-terrestrial crab Pachygrapsus marmoratus: an information-theory approach
Scientia Marina, 2007 The patterns of allometric growth of the grapsid crab Pachygrapsus marmoratus were investigated with an information-theoretic approach. This approach is beneficial, more robust, and may reveal more information than the classical approaches (e.g ...
Nikos Prototapas +3 more
doaj +1 more source
Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3
FEBS Open Bio, EarlyView.PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno +12 more
wiley +1 more source