Results 71 to 80 of about 168,262 (369)
Climate-Related Default Probabilities
RisksClimate risk refers to the risks associated with climate change and has already started to impact various sectors of the economy. In this work, we focus on the impact of physical risk on the probability of default for a firm in the agribusiness sector ...
Augusto Blanc-Blocquel +2 more
doaj +1 more source
Cloração de esgoto sanitário: variação de cloro residual e o uso de parâmetros facilmente mensuráveis na indicação de breakpoint [PDF]
Revista DAE, 2017 Neste estudo, foram monitoradas as variações de cloro residual livre e combinado após aplicação de cloro em diferentes dosagens e tempos de contato em esgoto advindo de tratamento preliminar. Em alguns casos, para um mesmo tempo de contato, houve maiores
Raphael Corrêa Medeiros +1 more
doaj +1 more source
Frontiers in Pharmacology, 2021 Nemonoxacin, a novel nonfluorinated quinolone for the treatment of community-acquired pneumonia. We reported the pharmacokinetic/pharmacodynamic (PK/PD) targets and PK/PD breakpoints of nemonoxacin against Streptococcus pneumoniae using a neutropenic ...
Xin Li +30 more
doaj +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Recombination in Hepatitis C Virus
Viruses, 2011 Hepatitis C virus (HCV) is a Flavivirus with a positive-sense, single-stranded RNA genome of about 9,600 nucleotides. It is a major cause of liver disease, infecting almost 200 million people all over the world.
María Alma Bracho +2 more
doaj +1 more source
PLoS Genetics, 2013 Gene fusions, like BCR/ABL1 in chronic myelogenous leukemia, have long been recognized in hematologic and mesenchymal malignancies. The recent finding of gene fusions in prostate and lung cancers has motivated the search for pathogenic gene fusions in ...
Craig P. Giacomini +17 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Rapid mapping of chromosomal breakpoints: from blood to BAC in 20 days [PDF]
, 2009 Structural chromosome aberrations and associated segmental or chromosomal aneusomies are major causes of reproductive failure in humans. Despite the fact that carriers of reciprocal balanced translocation often have no other clinical symptoms or ...
Baumgartner, Adolf +7 more
core +2 more sources
Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou +12 more
wiley +1 more source
The Catching up Processes of the Regions of the Visegrad Group Countries
Comparative Economic Research, 2018 The majority of Central and Eastern European post‑socialist countries acceded to the European Union in 2004. The integration of these economies to the Union had begun earlier, which was strengthened by grants from the Structural Funds after the accession.
Imre Lengyel, Balázs Kotosz
doaj +1 more source