Results 81 to 90 of about 127,476 (326)

Revealing Cell‐Free Mitochondrial DNA Breakage Patterns as Novel Biomarkers for Sepsis

open access: yesAdvanced Science, EarlyView.
Uncovering distinct plasma cfmtDNA breakage patterns opens new frontiers for early sepsis detection and prognosis. Unique cleavage hotspots in RNR2 and COX2 regions outperform traditional biomarkers, while mechanistic insights suggest bacterial endonuclease involvement.
Haitang Liao   +13 more
wiley   +1 more source

The where and wherefore of evolutionary breakpoints [PDF]

open access: yesJournal of Biology, 2009
The 'action' in genome-level evolution lies not in the large gene-containing segments that are conserved among related species, but in the breakpoint regions between these segments. Two recent papers in BMC Genomics detail the pattern of repetitive elements associated with breakpoints and the epigenetic conditions under which breakage occurs.
openaire   +3 more sources

A Natural Major Module Confers the Trade‐Off between Phenotypic Mean and Plasticity of Grain Chalkiness in Rice

open access: yesAdvanced Science, EarlyView.
This study reveals the genetic and molecular mechanisms controlling the general trade‐off between phenotypic mean and plasticity of grain chalkiness in rice and identifies two major external drivers (high temperature and wide grain) and a natural major module (GCP6‐MPC5) that control this trade‐off.
Juncheng Zhang   +10 more
wiley   +1 more source

Dynamic Neural Deactivation Bridges Direct and Competitive Inhibition Processes

open access: yesAdvanced Science, EarlyView.
Dynamic neural deactivation bridges traditionally distinct inhibitory mechanisms—direct inhibition and competition‐induced inhibition—revealing a common neural signature across modalities. Multimodal neuroimaging and behavioral experiments demonstrate a temporal dynamic characterized by progressive frontoparietal activation decay and enhanced sensory ...
Zhenhong He   +6 more
wiley   +1 more source

Photobreeding Method for Direct Construction and Continuous Tuning of Strong Metal–Support Interactions at Room Temperature

open access: yesAdvanced Science, EarlyView.
A photobreeding strategy enables the room‐temperature construction of strong metal–support interactions (SMSI) on Zn0.8Cd0.2S, achieving both direct SMSI formation and continuous interfacial tuning. UV‐induced photoreduction of Zn2+ generates metallic Zn, which is subsequently encapsulated by CdS, offering tunable and enhanced catalytic performance ...
Wei‐Qiang Huang   +3 more
wiley   +1 more source

GLM7 – A Novel Composite Glycolipid Index Derived from Routine Health Indicators for Enhanced Diagnosis and Prediction of Multimorbidity

open access: yesAdvanced Science, EarlyView.
This study leverages NHANES data to analyze 49 routine indicators, identifying the top 10 diagnostic markers for five major diseases and introducing GLM7, a novel indicator. Restricted cubic spline analyses, forest plot evaluations, and XGBoost modeling demonstrate conventional indicators' efficacy and GLM7's value for disease diagnosis/prediction ...
Zhihua Wang   +8 more
wiley   +1 more source

novoBreak: local assembly for breakpoint detection in cancer genomes. [PDF]

open access: yes, 2017
We present novoBreak, a genome-wide local assembly algorithm that discovers somatic and germline structural variation breakpoints in whole-genome sequencing data.
Boutros, Paul   +10 more
core  

Price Transmission During Promotions: A Case Study of Spanish Milk Brands

open access: yesAgribusiness, EarlyView.
ABSTRACT Price promotion is the marketing tool typically used by retail brands to boost sales and gain market share. In this paper, we intend to investigate the price transmission mechanism among competitive brands in Spain when price reductions that are associated with price promotions take place.
Yasmine Bedoui   +2 more
wiley   +1 more source

BCR (breakpoint cluster region) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on BCR (breakpoint cluster region), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire   +3 more sources

Thermal stability of some aircraft turbine fuels derived from oil shale and coal [PDF]

open access: yes
Thermal stability breakpoint temperatures are shown for 32 jet fuels prepared from oil shale and coal syncrudes by various degrees of hydrogenation.
Reynolds, T. W.
core   +1 more source

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