Results 71 to 80 of about 2,376 (166)

Early Diagnosis of Herpes Zoster Neuralgia: A Narrative Review

Pain and Therapy, 2023
Background Early intervention reduces the incidence of postherpetic neuralgia (PHN). Typical shingles are easy to diagnose; however, there is no clear diagnostic method for neuralgia symptoms manifested before the onset of the rash, which can easily ...
Han-Rui Fan, En-Ming Zhang, Yong Fei, Bing Huang, Ming Yao   +4 more
doaj   +1 more source

A Phase 2 Trial of Frexalimab, a CD40L Antagonist, in Adolescents and Adults With Recent‐Onset Type 1 Diabetes (FABULINUS): Rationale and Study Design

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Introduction Type 1 diabetes (T1D) is a chronic autoimmune disease, characterised by progressive destruction of the insulin‐producing pancreatic β‐cells. Preserving remaining β‐cells at the time of diagnosis may improve long‐term outcomes. Frexalimab is a humanised monoclonal antibody specific for CD40L undergoing evaluation for treatment of ...
Andriy Cherkas, Baerbel Rotthaeuser, Niels Porksen, Pascale Labard, My‐Liên Nguyên‐Pascal, Mathieu Coudert, Baptiste Berthou, Marie Baccara‐Dinet, Gabor Boka, Mark Peakman, Felix Reschke, Michael J. Haller   +11 more
wiley   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Therapy With Doxycycline and Hydroxychloroquine Enables Surgical Excision of Ulcerated Cutaneous Granulomas in a Patient With Ataxia Telangiectasia

Pediatric Dermatology, EarlyView.
ABSTRACT The rubella virus vaccine strain can cause granulomas in patients with inborn errors of immunity that may evolve into chronic, recalcitrant ulcers. This report details treatment of ulcerated rubella granulomas in a patient with ataxia telangiectasia with doxycycline and hydroxychloroquine resulting in partial ulcer healing within 4 weeks ...
Luis Murguía‐Favela, Sofia Maruschak‐Love, Robertson A. Harrop, Marie‐Anne Brundler, Kyle Kurek, Kevin Fonseca, Michele L. Ramien   +6 more
wiley   +1 more source

Joint Effects of Prenatal Antibiotics, Mode of Birth and Breastfeeding Duration on Childhood Infections: The Norwegian MoBa Cohort Study

Paediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background Prenatal antibiotic exposure and caesarean births are associated with an increased risk of hospitalised infection in children, but few studies have evaluated their impact on less severe infections and possible joint effects. Conversely, longer breastfeeding duration is protective against infections, but whether this effect varies ...
Isobel M. F. Todd, Lars Henning Pedersen, Jessica E. Miller, David P. Burgner, Maria C. Magnus   +4 more
wiley   +1 more source

Overview of varicella dynamic transmission model structure.

, 2019
The left column of compartments represents the natural history and evolution of natural varicella through wild-type HZ (zoster). The other two columns represent the natural history following varicella vaccination with the center column flowing from ...
Matthew Pillsbury (4633690), Ener Cagri Dinleyici (7224638), Cuneyt Yardimci (7224632), Zafer Kurugöl (7224629), Lara J. Wolfson (7224623), Vincent J. Daniels (7224626), Jeffrey Kyle (7224635)   +6 more
core   +1 more source

Living in the Mycelial World

Topics in Cognitive Science, EarlyView.
Abstract This manuscript documents a systematic ethnomycological analysis of ethnographic archives. Focusing on texts describing human–fungi interactions, I conduct a global, cross‐cultural review of mushroom use, covering 193 societies worldwide. The study reveals diverse mushroom‐related cultural practices, emphasizing the significance of fungi ...
Roope O. Kaaronen
wiley   +1 more source

Characterisation of immune responses to varicella vaccination in relation to clinical outcome

, 2010
PhDThis thesis examines both humoral and cellular adaptive immune responses to varicella vaccination (up to 18 months post immunisation), in an ethnically diverse population of healthcare workers.
McDonald, Suzanna Leonie Rose
core  

Schematic representation of the model. Natural varicella and HZ.

, 2013
M represents individuals protected by maternal antibodies; VS, VE, VI represent varicella susceptible, latent and infective; VR represents individuals recovered from varicella and temporally protected by CMI against HZ; ZS, ZI, ZR represent individuals ...
Piero Poletti (130294), Emanuele del Fava (5654617), Alessia Melegaro (201035), Marco Ajelli (42327), Pierluigi Lopalco (403327), Giampaolo Scalia Tomba (403326), Stefano Merler (42326), Giorgio Guzzetta (100661), Piero Manfredi (42329), Luca Faustini (403325), Caterina Rizzo (38390)   +10 more
core   +1 more source

Women in space: A review of known physiological adaptations and health perspectives

Experimental Physiology, EarlyView.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford, Danielle J. Carroll, Heather C. M. Allaway, Bonnie J. Dunbar, Aenor J. Sawyer   +4 more
wiley   +1 more source