Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Droplet size spectrum, velocity, angle and flow rate of pulse-width-modulated spray nozzles with adjuvants. [PDF]
da Cunha JPAR, Ozkan E, Jeon H, Zhu H.
europepmc +1 more source
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Efficacy of rebamipide for the treatment of dry eye disease: An updated meta-analysis of randomized and non-randomized controlled trials. [PDF]
Murtaza M +9 more
europepmc +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Numerical Investigation of Downstream-Shaft Aeration and Air-Pocket Evolution in a Navigation-Lock Valve. [PDF]
Xie T, Li Z, Yan X, Deng J, Xu D.
europepmc +1 more source
Acute tear-film disruption in treatment-naive acute anterior uveitis: A retrospective case-control study. [PDF]
Zhang Z, Fang C, Li B.
europepmc +1 more source
Effect of a One-Week Lubricant Pretreatment on Post-LASIK Dry Eye: Single-Center Randomized, Single-Masked Study With 1-Month Follow-Up. [PDF]
Cañones-Zafra R +3 more
europepmc +1 more source
Turing-driven spiral defect chaos with stationary spiral tips: universal criticality in a time-discrete oscillatory system. [PDF]
Wang Q, Gao J.
europepmc +1 more source
Fluorescein tear breakup time predicts pre-lens tear film stability and contact lens comfort. [PDF]
Lin CH +5 more
europepmc +1 more source

