Results 51 to 60 of about 29,256 (309)

Experimental and Numerical Study on Flow Resistance and Bubble Transport in a Helical Static Mixer

Energies, 2020
Flow resistance and bubble transport in a helical static mixer were studied experimentally and numerically. The inline mixer increases the volume fraction of gas in liquids by breaking bubbles into smaller sizes with a micrometer size in the flow ...
Fangyang Yuan, Zhengwei Cui, Jianzhong Lin   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

ASSESSING THE INFLUENCE OF THE AL WAHDA DAM COMMISSIONING ON FLOOD FLOWS AND LOW WATER LEVELS IN THE GHARB PLAIN, MOROCCO

Zbornik Radova: Geografski institut "Jovan Cvijić"
The Sebou Basin is one of the most important hydrographic basins in Morocco. When the Wadi Sebou enters the Gharb Plain, it encounters difficulties in evacuating its waters during wet years due to its flattening, resulting in risks of floods.
Driss El Karfa, Jamal Al Karkouri, Mouhcine Batchi, Hommane Boudine   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Evolution From Past to Future Conditions of Fast Ice Coverage in James Bay

Frontiers in Earth Science, 2019
Fast ice is often used by coastal communities in the James Bay area for transportation in winter using snowmobiles. Therefore, the extent of fast ice along the James Bay coastline is important for land use and any changes to these extents may have ...
Wael Taha, Maryse Bonneau-Lefebvre, Arian Cueto Bergner, Alain Tremblay   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Young Love: Romantic Concerns and Associated Mental Health Issues among Adolescent Help-Seekers

Behavioral Sciences, 2016
Over 50% of young people have dated by age 15. While romantic relationship concerns are a major reason for adolescent help-seeking from counselling services, we have a limited understanding of what types of relationship issues are most strongly related ...
Megan Price, Leanne Hides, Wendell Cockshaw, Aleksandra A. Staneva, Stoyan R. Stoyanov   +4 more
doaj   +1 more source