Results 51 to 60 of about 2,128,083 (309)

A Cross-Sectional Study of Breast Cancer Surgery and the Cost Based on Data From 77 Chinese 3A Hospitals in 2015

Frontiers in Oncology, 2022
PurposesWe aimed to clarify the real-world status of breast cancer surgery and the cost in China.MethodsThis cross-sectional survey relied on data obtained from the hospitalization summary reports (HSRs) in 77 top-ranked (grade 3A) hospitals in China to ...
Rong Zhao, Meng Jin, Jinnan Gao, Linhui Zhang, Liyuan Tao, Liyuan Tao, Xiaoyuan Bao   +6 more
doaj   +1 more source

Breast conservative surgery and local recurrence

The Breast, 2015
Breast conservation is a legacy of Umberto Veronesi who laid the groundwork for the preservation of the body image of women affected by breast cancer (BC) with the Milan I study in the late 70ies of the last millennium. Breast conservative surgery (BCS) has two aspects: oncological safety of tumour resection with free margins and aesthetic preservation
Rezai, Mahdi, Kraemer, Stefan, Kimmig, Rainer, Kern, Peter   +3 more
openaire   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Predictive factors for breast conserving surgery after neoadjuvant chemotherapy in breast cancer

World Journal of Surgical Oncology
Background Neoadjuvant chemotherapy has several advantages, including reducing the number of mastectomies. Breast conserving surgeries avoid certain complications and sequelae, reduces hospital stays and improves patients’ quality of life and aesthetics.
Julie Berna, Sophie Michel, Leila Bouazzi, Vivien Ceccato, Lauren Darrigues, Elodie Gauroy, Enora Laas, Julie Rosa, Emilie Raimond, Imane Menouer, Olivier Graesslin, Thomas Gaillard, Fabien Reyal, Coralie Barbe, Judicael Hotton   +14 more
doaj   +1 more source

Breast conservation and oncoplastic surgery are associated with improved quality of life

Frontiers in Oncology
IntroductionLocal treatment can be distressful to breast cancer patients. We aimed to evaluate how different types of local treatment impact the quality of life of patients.MethodsIn this retrospective cohort study, one-year postoperative Breast-Q ...
Daniel Barbalho, Natalia Polidorio, Lincon Mori, Alfredo Barros, Marcelo Sampaio, Sandro Melo, Amilcar Assis, Pamela Bioni, Giovanna Miziara, Murilo Fraga, Felipe Andrade   +10 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Breast Conservation Surgery: State of the Art

International Journal of Breast Cancer, 2011
Breast conservation surgery is available to the vast majority of women with breast cancer. The combination of neoadjuvant therapies and oncoplastic surgical techniques allows even large tumours to be managed with a breast-conserving approach. The relationship between breast size and the volume of tissue to be excised determines the need for volume ...
Jonathan White, Raj Achuthan, Philip Turton, Mark Lansdown   +3 more
openaire   +3 more sources

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Value of intra-operative ultrasound in localization of palpable or non-palpable breast tumors during breast conserving surgery

The Egyptian Journal of Radiology and Nuclear Medicine, 2018
Purpose: Our study was designed to assess the role of intra-operative ultrasound (IOUS) as a method of localization of palpable or non-palpable breast tumors during breast conserving surgery (BCS) and ensuring adequate margins by comparing pathological ...
Shorouk Zaky Abdel Aziz Abdelshafy, Medhat Mohamed Refaat, Gamal Elsayed Saleh, Mohammed I. Yousef   +3 more
doaj   +1 more source

Recurrence after breast conserving surgery; can re-excision with intraoperative margin assessment normalize the risk of local recurrence? [PDF]

Ain-Shams Journal of Surgery, 2009
Background: Breast conserving therapy (BCT), including breast conserving surgery (BCS) and radiotherapy has become the preferred method of treatment for early stage breast cancer.
Ayman M S Soliman, Yasser Abdel Reheem, Osama M El-Shiekh, Ahmed M Awad Ellakany, Hala Rashad   +4 more
doaj   +1 more source