Results 111 to 120 of about 183,524 (300)

A Functionally Conserved Enhancer is Critical for PGC1A Expression and Thermogenesis in Brown Fat

open access: yesAdvanced Science, EarlyView.
An evolutionarily conserved enhancer controls PGC1A expression and thermogenic activation in brown adipose tissue. Integrative multi‐omics analyses identify two BAT‐specific enhancers, with PGC1A‐En1 functioning as the dominant regulatory element that maintains thermogenic capacity across species.
Duo Su   +10 more
wiley   +1 more source

Evaluation of Breast Feeding Practices

open access: yesGomal Journal of Medical Sciences, 2004
Background: The best first food for babies is breast milk. This study was conducted to assess the percentage of population having knowledge regarding benefits of breast feeding, exclusive breast feeding and ratio of mothers practicing it.
Naheed Parveen   +2 more
doaj  

Engineered Bacteria Factory Integrating Drug Delivery and Antibody Manufacture for Activating the STING Signal Pathway Mediated Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
To address the limitations of protein‐based ICIs in applications, this study constructed an engineered bacterium, HRB, capable of expressing aCD47 in hypoxic TME. Through the Schiff base reaction, responsive liposomes (LC) loaded with the STING agonist cGAMP were connected to the surface of bacteria to form HRB@LC.
Peng‐Shuo Dong   +9 more
wiley   +1 more source

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason   +12 more
wiley   +1 more source

Evaluation of factors influencing on non-exclusive breast feeding during the first six months of life in Bushehr Port using focus group discussion

open access: yesIranian South Medical Journal, 2004
Non-exclusive breast feeding in the early years of life is one of the most important factors in growth and development of infants. Therefore, exclusive breast feeding is recommended during the first six months of life.
Sherafat Akaberian, Mahin Dianat
doaj  

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang   +9 more
wiley   +1 more source

COMPLICATIONS OF INTRAUTERINE DEVICE (I.U.D) AND ITS’ IMPACTS ON BREAST FEEDING PERIOD AT THE TIME OF PLACEMENT

open access: yesنشریه پرستاری ایران, 2002
Background: Placing I.U.D is a very effective method in the prevention of pregnancy, which has increasingly became popular. Women have found it an effective, safe and comfortable method all over the world.
Ghorbani, S   +3 more
doaj  

Challenging the utility of 24-hour recall of exclusive breast feeding in Japan. [PDF]

open access: yesBMJ Glob Health, 2023
Nanishi K   +5 more
europepmc   +1 more source

THE IMPACT OF COUNSELING OF EARLY BREAST-FEEDING INITIATION ON DELIVERY MOTHERS IN PARE PARE CITY SOUTH SULAWESI, INDONESIA [PDF]

open access: yes
The aims of the research are to assess the difference between the knowledge and attitude of \ud delivery mothers before intervention and the one after intervention, to assess the delivery \ud mothers??? practice in giving early
Suriah
core  

Breastfeeding education: where are we going? A systematic review article [PDF]

open access: yes, 2016
Background: UNICEF (United Nations International Children’s Emergency Fund) and WHO estimate that if all babies were breastfed for at least the first six months of their lives, the rate of morbidity and malnutrition would sig-nificantly decrease all over
Ban Frangež, Helena   +7 more
core  

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