Results 151 to 160 of about 3,052,066 (346)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Breast reconstruction.

open access: yesExperimental oncology, 2014
Mastectomy has been used for the treatment of breast cancer for many years, but the importance of the positive psychosocial benefits of breast reconstruction in breast cancer treatment has been recognized in the past years. Now, more women seek breast reconstruction and surgeons perform more reconstructions. A breast can be reconstructed by two methods:
Kaya, B., Serel, S.
openaire   +2 more sources

Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update.

open access: yesJournal of Clinical Oncology, 2013
Antonio C. Wolff   +19 more
semanticscholar   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety [PDF]

open access: bronze, 2015
Sang Jun Han   +8 more
openalex   +1 more source

Breast Cancer and Breast-Feeding [PDF]

open access: yesCA: A Cancer Journal for Clinicians, 1982
openaire   +2 more sources

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer.

open access: yesNew England Journal of Medicine, 2004
S. Paik   +17 more
semanticscholar   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Agreement Among Breast Cancer Screening Modalities in Breast Density Assessment and Cancer Risk Prediction. [PDF]

open access: yesInt J Breast Cancer
Aloufi AS   +6 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy