Results 191 to 200 of about 3,052,066 (346)
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama +7 more
wiley +1 more source
Prospective Breast Cancer Biomarkers Identified Using miR-526b-Driven Metabolic Alterations. [PDF]
Nault B, Majumder M.
europepmc +1 more source
Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study.
L. Carey +16 more
semanticscholar +1 more source
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
High levels of circulating miR-19a-3p in patients with metastatic HER2 + breast cancer are associated with a favorable prognosis and anti-tumor immune responses. [PDF]
Cohen EN +8 more
europepmc +1 more source
Breast Inflammation Mimicking Breast Cancer on Multimodality Breast Imaging
Mahbod Jafarvand Giglou, Habib Rahbar
openaire +2 more sources
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source
Táticas cirúrgicas nos explantes mamários
Ricardo Eustáchio de Miranda
doaj +1 more source

