Results 221 to 230 of about 3,479,769 (339)

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Influence of Maternal Glycemia on Breast Milk Composition and Volume Ingested by Infants of Mothers With Type 1 Diabetes. [PDF]

Diabetes Care
Donovan LE, Bell RC, Yamamoto JM, Lemieux P, Ho J, Feig DS, Virtanen H, Crawford S, Reimer RA.   +8 more
europepmc   +1 more source

Bilateral adrenalectomy in the palliation of metastatic breast cancer [PDF]

, 1957
Mortimer B. Lipsett, Willet F. Whitmore, Norman Treves, Charles D. West, Henry T. Randall, Olof H. Pearson   +5 more
openalex   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

Chest Wall Perforator Flaps in Partial Breast Reconstruction: A Systematic Review and Meta-analysis. [PDF]

Plast Reconstr Surg Glob Open
Nava CM, Zinner G, Martineau J, Oranges CM.   +3 more
europepmc   +1 more source

Breast cancer and its diagnosis and treatment [PDF]

, 1956
Louis M. Hellman
openalex   +1 more source

High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer

FEBS Open Bio, EarlyView.
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson, Lisa Lif, Husam Oda, Alexandra Lorenzzi de Melo, David Lindquist, Håkan Hedman   +5 more
wiley   +1 more source

Comprehensive analysis of the PLXNA3 gene on prognosis and immune characteristics in breast cancer. [PDF]

Sci Rep
Sun W, Xu Y, Qi Q, Zhang W, Pan H, Sun G, Wang S, Zhou W.   +7 more
europepmc   +1 more source

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

FEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source

Identification of copper related biomarkers in breast cancer using machine learning. [PDF]

Discov Oncol
Wang J, Wang H, Li Z, Xu Q, Yang Y, Shi R, Liu F, Jin S.   +7 more
europepmc   +1 more source