Results 281 to 290 of about 3,479,769 (339)

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Minimally invasive biopsy technique predicting breast pathological complete response after neoadjuvant therapy for breast cancer. [PDF]

Gland Surg
Shi Z, Qiu P, Wang Y, Liu H.
europepmc   +1 more source

Eco‐Fabricated Nanowave‐Textured Implants Drive Microtubule‐Assisted Nuclear Mechanotransduction and Chromatin Modification: Biophysical Priming for Osteogenesis and Bone Regeneration

Advanced Functional Materials, EarlyView.
Eco‐friendly nanowave‐textured implants produced via femtosecond laser fabrication enhance bone regeneration by orchestrating a precise mechanotransduction cascade. This nanotopography directs mesenchymal stem cell alignment and cytoskeletal organization, triggering changes in nuclear shape and chromatin acetylation that prime cells for osteogenesis ...
Bosu Jeong, Ji‐Young Yoon, Junyong Ahn, Byunghak Lee, Sung‐Min Park, Jae‐Heon Kim, Buuvee Bayarkhangai, Yu Jin Kim, Sak Lee, Jonathan C. Knowles, Moon‐Young Kim, DongJun Lee, Sang‐Hoon Rhee, Hae‐Hyoung Lee, Hae‐Won Kim, Jung‐Hwan Lee   +15 more
wiley   +1 more source

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source

Rationally Designed Carbon Nanomaterials for Electrically Driven Solid‐State Hydrogen Storage

Advanced Functional Materials, EarlyView.
A bottom‐up design principle integrating atomic‐level and nanoscale structural engineering is developed to guide the rational design of electrically tunable, solid‐state hydrogen storage materials that enable non‐dissociative chemisorption under applied electric fields.
Yong Gao, Panyu Gao, Chao Li, Qiuyan Yue, Qing Liang, Sifan Qiao, Wei Zhang, Weitao Zheng, Lipeng Zhang, Zhenglong Li, Wen‐Gang Cui, Xiaowei Wang, Yiyang Wan, Mingchang Zhang, Xinqiang Wang, Yanxia Liu, Fulai Qi, Chenchen Li, Jian Miao, Jing Zhang, Xiao Han, Pan Wang, Chang Guo, Qiao Chen, Ziyuan Xu, Mingxia Gao, Wenping Sun, Yaxiong Yang, Jian Chen, Zhenhai Xia, Hongge Pan   +30 more
wiley   +1 more source

Cholesterol in mRNA‐Lipid Nanoparticles can be Replaced with the Synthetic Mycobacterial Monomycoloyl Glycerol Analogue MMG‐1

Advanced Functional Materials, EarlyView.
This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras, Saahil S. Baghel, Rune F. Jensen, Aneesh Thakur, Henrik Franzyk, Oskar Thofte, Marco Herrera‐Barrera, Madeleine Landry, Melike Ongun, Ahmad Tami, Marlene P. Thanthrige, Eva Callens, Corinne Beinat, Thomas Rades, Søren R. Paludan, Kristian Riesbeck, Ida Rosenkrands, Dennis Christensen, Gabriel K. Pedersen, Camilla Foged   +19 more
wiley   +1 more source

Metal Nanoclusters for Cancer Imaging and Treatment

Advanced Functional Materials, EarlyView.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu, Ziping Wang, Qiaofeng Yao, Ping Zhang, Jianping Xie, Xun Yuan   +5 more
wiley   +1 more source

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

Advanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao, Tong Ye, Mingjiang Liu, Jingchao Gao, Lian Tan, Qian Dong, Qingbo Lv, Qianqian Ye, Yu Wang   +8 more
wiley   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source