Results 91 to 100 of about 66,018 (333)

GRP78 Nanobody‐Directed Immunotoxin Activates Innate Immunity Through STING Pathway to Synergize Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
A GRP78 nanobody‐directed immunotoxin suppresses cancer progression and metastasis by enhancing antitumor immunity via STING pathway activation, offering a pan‐cancer‐targeted approach and immunotherapy combination strategy. Abstract The lack of targetable antigens poses a significant challenge in developing effective cancer‐targeted therapies.
Huifang Wang   +16 more
wiley   +1 more source

DCGANs for Realistic Breast Mass Augmentation in X-ray Mammography [PDF]

open access: yesarXiv, 2019
Early detection of breast cancer has a major contribution to curability, and using mammographic images, this can be achieved non-invasively. Supervised deep learning, the dominant CADe tool currently, has played a great role in object detection in computer vision, but it suffers from a limiting property: the need of a large amount of labelled data ...
arxiv  

The waterfall effect in breast augmentation [PDF]

open access: yesGland Surgery, 2017
The 'waterfall effect' is a descriptive term to indicate a sliding ptosis of parenchymal breast tissue over a fixed or encapsulated implant. It occurs more frequently than surgeons anticipate and especially over the longer term after augmentation. Certain breast implants are more prone to contribute to this problem as are implants placed in submuscular
openaire   +3 more sources

PCSK9 Promotes the Malignancy of Triple‐negative Breast Cancer Cells by Reducing Cholesterol Levels at the Plasma Membrane to Activate EGFR and HER3

open access: yesAdvanced Science, EarlyView.
By decreasing cholesterol and lipid raft levels in the plasma membrane, proprotein convertase subtilisin/kexin type 9 (PCSK9) boosts human epidermal growth factor receptor 1 and 3 (EGFR and HER3) activation, driving tumor growth and metastasis in triple‐negative breast cancer (TNBC).
Tianhong Li, Renfei Wu, Kathy Qian Luo
wiley   +1 more source

Augmentation mammoplasty, irradiation, and breast cancer.A case report [PDF]

open access: bronze, 1975
Paul T. Frantz, Charles A. Herbst
openalex   +1 more source

Augmentation of the ptotic breast: Simultaneous periareolar mastopexy/breast augmentation** [PDF]

open access: yesAesthetic Surgery Journal, 1999
Background: Submusculofascial augmentation of the ptotic breast can result in a “double-bubble”appearance, because a submusculofascial implant will lay superior to the ptotic gland. Subglandular augmentation in a ptotic breast avoids a “double-bubble” but will aggravate the preexisting ptosis.
openaire   +2 more sources

Epithelial Cell Mechanoresponse to Matrix Viscoelasticity and Confinement Within Micropatterned Viscoelastic Hydrogels

open access: yesAdvanced Science, EarlyView.
Extracellular matrix (ECM) viscoelasticity and spatial confinement regulate cellular processes such as cancer progression, yet their interplay remains poorly understood. By developing fibronectin (FN)‐micropatterned viscoelastic hydrogels mimicking breast cancer mechanics, this study explores breast epithelial cell mechanoresponse to ECM ...
Giuseppe Ciccone   +6 more
wiley   +1 more source

A tree augmented naive Bayesian network experiment for breast cancer prediction [PDF]

open access: yesarXiv, 2015
In order to investigate the breast cancer prediction problem on the aging population with the grades of DCIS, we conduct a tree augmented naive Bayesian network experiment trained and tested on a large clinical dataset including consecutive diagnostic mammography examinations, consequent biopsy outcomes and related cancer registry records in the ...
arxiv  

FGF2 Mediated USP42‐PPARγ Axis Activation Ameliorates Liver Oxidative Damage and Promotes Regeneration

open access: yesAdvanced Science, EarlyView.
USP42 is identified as a novel DUB of PPARγ in hepatocytes. USP42 mediated PPARγ deubiquitylation determines its transcriptional preference on proliferative and redox balance genes. USP42 knockdown exacerbates liver damage and delays regeneration. FGF2 is the upstream signal that initiates and activates the USP42‐PPARγ axis.
Nanfei Yang   +16 more
wiley   +1 more source

Case of late hematoma after breast augmentation

open access: yesArchives of Plastic Surgery, 2018
We present a case report of a patient who experienced a late, spontaneous breast hematoma 26 years after primary breast augmentation. Late hematomas are a rare complication of breast augmentation with uncertain etiology. In this case, there was no trauma,
Leslie Kim   +2 more
doaj   +1 more source

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