Results 131 to 140 of about 66,018 (333)

COPS5 Triggers Ferroptosis Defense by Stabilizing MK2 in Hepatocellular Carcinoma

Advanced Science, EarlyView.
COPS5, which is overexpressed in HCC in an amplification‐ and ATF4‐dependent manner, stabilizes MK2 through deubiquitination and, in turn, induces HSPB1 activation, protecting HCC cells from ferroptosis and thus promoting sorafenib resistance and tumor progression. Abstract Sorafenib, which is proven to serve as a potent ferroptosis inducer, is used as
Ai‐Ling Luo, Wen‐Ying Zheng, Qiong Zhang, Yan Yuan, Mei‐Qi Li, Kai Du, An‐Ran Gao, Li‐Jun Pei, Jie Xie, Wen‐Hao Chen, Long Zhang, Xiu‐Zhu Guo, Xiao‐Ran Yang, Chao Zeng, Guo‐Hua Yang, Min Deng   +15 more
wiley   +1 more source

Methocarbamol: Adjunct therapy for pain management in breast augmentation [PDF]

, 2002
Marc S. Schneider
openalex   +1 more source

Targeting PFKFB4 Biomimetic Codelivery System Synergistically Enhances Ferroptosis to Suppress Small Cell Lung Cancer and Augments the Efficacy of Anti‐PD‐L1 Immunotherapy

Advanced Science, EarlyView.
In this study, a targeting PFKFB4 biomimetic codelivery system is developed to improve paclitaxel efficacy by inducing ferroptosis in SCLC. This system enhances immune cell infiltration and cytokine secretion, activating anti‐tumor immunity. Combined with anti‐PD‐L1, it boosts immune responses, offering a novel therapeutic strategy for overcoming ...
Xiang Liu, Jingjun He, Haoxuan Ying, Cuiying Chen, Chongyang Zheng, Peng Luo, Weiliang Zhu, Ting Wei, Bufu Tang, Jian Zhang   +9 more
wiley   +1 more source

Evaluation of immune response to anti‐COVID‐19 booster in cancer patients and chronic medical cannabis users and its association with circulating Eosinophils levels

, 2022
Cancer Communications, Volume 42, Issue 12, Page 1417-1420, December 2022.
Cohen Idan, Campisi‐Pinto Salvatore, Rozenberg Orit, Abaev Ariel, Khoury Marah, Agbaria Dana, Eitam Harel, Colodner Raul, Khoury Mona, Shalabna Hassan, Samih Yousef, Mahamid Camel, Abu‐Amna Mahmoud, Bar‐Sela Gil   +13 more
wiley   +1 more source

Does breast augmentation confer risk of or protection from suicide? [PDF]

, 2003
Thomas E. Joiner
openalex   +1 more source

A Novel Breast Ultrasound Image Augmentation Method Using Advanced Neural Style Transfer: An Efficient and Explainable Approach [PDF]

arXiv
Clinical diagnosis of breast malignancy (BM) is a challenging problem in the recent era. In particular, Deep learning (DL) models have continued to offer important solutions for early BM diagnosis but their performance experiences overfitting due to the limited volume of breast ultrasound (BUS) image data.
arxiv  

Targeting Antigen‐Presenting Cells to Enhance the Tumor‐Spleen Immunity Cycle through Liposome‐Neoantigen Vaccine

Advanced Science, EarlyView.
LNPsD18, a cationic liposome that enhances antigen‐presenting cell uptake in the spleen and tumor without targeting ligands is developed. Co‐delivering neoantigens and a TLR9 agonist significantly improve DC activation, tumor immunity, and survival in liver and colorectal cancer models, demonstrating the importance of dual‐site APC targeting for cancer
Yu Xu, Bing Wang, Yue Huang, JianPing Liao, Chenyi Wu, Chenxi Zhou, Zishi Kang, Shiyang Jiang, Bing‐Chen Wu, Da Zhang, Ruihua Xu, Xiaolong Liu, Feng Wang   +12 more
wiley   +1 more source

Pharmacokinetics and Bioequivalence of Fudosteine in Healthy Chinese Volunteers Under Fasting and Fed Conditions: A 4‐Way Replicate Crossover Study

Clinical Pharmacology in Drug Development, Volume 12, Issue 1, Page 30-37, January 2023., 2023
Abstract The bioequivalence of a generic fudosteine tablet vs a brand‐named fudosteine tablet under fasting and fed conditions was evaluated in this study. This randomized, open‐label, single‐dose, 4‐way replicate, crossover, bioequivalence study included 64 healthy Chinese subjects (fasting cohort, n = 32; fed cohort, n = 32) who were assigned to ...
Mingxue Zhu, Yi Tao, Junliang Pu, Hongtao Zhao, Lei Wan, Peilin Zhang, Chengyong Tang   +6 more
wiley   +1 more source

Breast Augmentation in Swyer Syndrome Patient

, 1970
Vika Tania, Aditya Wardhana
openalex   +1 more source

STING Agonists and How to Reach Their Full Potential in Cancer Immunotherapy

Advanced Science, EarlyView.
STING agonists show promise in preclinical studies in boosting an anti‐tumor response using the immune system. However, different limitations remain, and future research is needed to better understand how STING activation impacts the tumor microenvironment, identify effective combination strategies, and determine the best tumor types for STING agonist ...
Laura Gehrcken, Christophe Deben, Evelien Smits, Jonas R.M. Van Audenaerde   +3 more
wiley   +1 more source