Results 281 to 290 of about 1,403,569 (408)

Engineering an Overflow‐Responsive Regulation System for Balancing Cellular Redox and Optimizing Microbial Production

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Escherichia coli accumulates acetate as a byproduct in fast growth aerobic conditions when using glucose as carbon source. This phenomenon, known as overflow metabolism, has negative impacts on cell growth and protein expression, also causes carbon loss during biosynthesis in most microbial production scenarios. In this study, we regarded the “
Jianli Zhang   +8 more
wiley   +1 more source

A Prospective, Randomized, Double-Blind, Controlled Trial of Continuous Local Anesthetic Infusion in Cosmetic Breast Augmentation

open access: bronze, 2008
Fereydoun Don Parsa   +5 more
openalex   +1 more source

Physiology and Robustness of Yeasts Exposed to Dynamic pH and Glucose Environments

open access: yesBiotechnology and Bioengineering, EarlyView.
The authors investigated how three Saccharomyces cerevisiae strains respond to dynamic substrate and pH oscillations using dynamic microfluidic single‐cell cultivation (dMSCC) and intracellular biosensors. By combining performance and robustness analysis of selected intracellular parameters, growth and morphological analysis, the authors identified ...
Luca Torello Pianale   +3 more
wiley   +1 more source

Temporal Galactose‐Manganese Feeding in Fed‐Batch and Perfusion Bioreactors Modulates UDP‐Galactose Pools for Enhanced mAb Glycosylation Homogeneity

open access: yesBiotechnology and Bioengineering, EarlyView.
This study investigates the temporal effects of galactose and manganese on the N‐glycosylation of Trastuzumab (mAb) antibody during fed‐batch and perfusion bioprocessing modes to reveal the influence of feeding schedules on mAb N‐glycosylation patterns. These findings will aid in building process control schemes for mAb bioprocessing.
Aron Gyorgypal   +4 more
wiley   +1 more source

Nanomaterials for enhanced X‐ray‐triggered cancer therapy: Progress and prospects

open access: yesBMEMat, EarlyView.
This review summarizes the latest progress in nanomaterials for X‐ray‐triggered cancer therapy, highlighting their various advantages such as targeted delivery, reduced side effects, and enhanced therapeutic efficacy. Abstract X‐rays, a form of ionizing radiation with high energy and significant penetration capability, are commonly used in clinical ...
Yuanchun Chen   +6 more
wiley   +1 more source

Oleomas mimicking cutaneous xanthomas following breast augmentation by injection of liquid silicone [PDF]

open access: green, 2014
MIGUEL ANTONIO GONZALEZ-SABIN   +3 more
openalex   +1 more source

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