Results 141 to 150 of about 2,749,776 (308)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Clinical practice guidelines for multigene assays in patients with early-stage breast cancer: Chinese Society of Breast Surgery (CSBrS) practice guidelines 2021

Chinese Medical Journal, 2021
Jiu-Jun Zhu, De-Chuang Jiao, Min Yan, Xu-Hui Guo, Ya-Jie Zhao, Xiu-Chun Chen, Cheng-Zheng Wang, Zhen-Duo Lu, Lian-Fang Li, Shu-De Cui, Zhen-Zhen Liu, Chinese Society of Breast Surgery, Yuan-Yuan Ji   +12 more
doaj   +1 more source

NREP, transcriptionally upregulated by HIF-1α, aggravates breast cancer cell growth and metastasis by promoting glycolysis

Cell Death Discovery
Breast cancer (BC) poses a great threat to women’s health. Neuronal regeneration related protein (NREP) is a multifunctional protein that is involved in embryonic development, regeneration, and human disease.
Yuxia Ruan, Jianghua Qiao, Jiabin Wang, Zhenzhen Liu   +3 more
doaj   +1 more source

When to order a biopsy to characterise a metastatic relapse in breast cancer [PDF]

, 2012
Theodoros Foukakis, Gunnar Åström, Linda S. Lindström, Thomas Hatschek, Jonas Bergh   +4 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Evaluating Preoperative Anxiety Levels in Patients Undergoing Breast Cancer Surgery

, 2020
Maria Katsohiraki, Sofia Poulopoulou, Nikolaos Fyrfiris, Ioannis Κoutelekos, Polyxeni Tsiotinou, Olga Adam, Eleni Vasilopoulou, Μαρία Καπρίτσου   +7 more
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Clinical practice guidelines for modified radical mastectomy of breast cancer: Chinese Society of Breast Surgery (CSBrs) practice guidelines 2021

Chinese Medical Journal, 2021
De-Chuang Jiao, Jiu-Jun Zhu, Li Qin, Xu-Hui Guo, Ya-Jie Zhao, Xiu-Chun Chen, Cheng-Zheng Wang, Zhen-Duo Lu, Lian-Fang Li, Shu-De Cui, Zhen-Zhen Liu, Yuan-Yuan Ji., Chinese Society of Breast Surgery   +12 more
doaj   +1 more source

Social cognitive influences on physical activity participation in long‐term breast cancer survivors

, 2012
Siobhan M. Phillips, Edward McAuley
openalex   +1 more source

MicroRNA‐409‐3p regulates cell invasion and metastasis by targeting ZEB1 in breast cancer [PDF]

, 2016
Zhenhai Ma, Yang Li, Jingchao Xu, Qiaozhen Ren, Jihong Yao, Xiaofeng Tian   +5 more
openalex   +1 more source