Results 141 to 150 of about 2,472,817 (358)

Investigation into the molecular mechanism of the antiapoptotic functions of CTCF in breast cancer cells using a proteomics approach [PDF]

, 2009
A Vostrov, CF Méndez-Catalá, D Farrar, E Klenova, E Pugacheva, EM Klenova, F Docquier, F Docquier, I Cherhukhin   +8 more
core   +2 more sources

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Clinical practice guidelines for multigene assays in patients with early-stage breast cancer: Chinese Society of Breast Surgery (CSBrS) practice guidelines 2021

Chinese Medical Journal, 2021
Jiu-Jun Zhu, De-Chuang Jiao, Min Yan, Xu-Hui Guo, Ya-Jie Zhao, Xiu-Chun Chen, Cheng-Zheng Wang, Zhen-Duo Lu, Lian-Fang Li, Shu-De Cui, Zhen-Zhen Liu, Chinese Society of Breast Surgery, Yuan-Yuan Ji   +12 more
doaj   +1 more source

Deep Transfer Learning for Breast Cancer Classification [PDF]

arXiv
Breast cancer is a major global health issue that affects millions of women worldwide. Classification of breast cancer as early and accurately as possible is crucial for effective treatment and enhanced patient outcomes. Deep transfer learning has emerged as a promising technique for improving breast cancer classification by utilizing pre-trained ...
arxiv  

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

LINC01235 Promotes Clonal Evolution through DNA Replication Licensing‐Induced Chromosomal Instability in Breast Cancer

Advanced Science
Despite the development of HER2‐targeting drugs such as trastuzumab and T‐DXd, treatment resistance is a substantial challenge, often leading to relapse and distant metastasis.
Qi Zhang, Xuliren Wang, Zhibo Shao, Yi Zhang, Liyi Zhang, Ming Chen, Xujie Zhou, Han Zhu, Yue Zhou, Xinya Lu, Pei Li, Weiru Chi, Lun Li, Zhi‐Ming Shao, Shenglin Huang, Jingyan Xue, Yayun Chi, Jiong Wu, Bingqiu Xiu   +18 more
doaj   +1 more source

Deep Learning Predicts Mammographic Breast Density in Clinical Breast Ultrasound Images [PDF]

arXiv
Background: Breast density, as derived from mammographic images and defined by the American College of Radiology's Breast Imaging Reporting and Data System (BI-RADS), is one of the strongest risk factors for breast cancer. Breast ultrasound (BUS) is an alternative breast cancer screening modality, particularly useful for early detection in low-resource,
arxiv  

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

NREP, transcriptionally upregulated by HIF-1α, aggravates breast cancer cell growth and metastasis by promoting glycolysis

Cell Death Discovery
Breast cancer (BC) poses a great threat to women’s health. Neuronal regeneration related protein (NREP) is a multifunctional protein that is involved in embryonic development, regeneration, and human disease.
Yuxia Ruan, Jianghua Qiao, Jiabin Wang, Zhenzhen Liu   +3 more
doaj   +1 more source

Lewison, Edward F.: Breast cancer; and its diagnosis and treatment. Baltimore. Williams & Wilkins Co. 1955. 478 pp. $ 15.00— [PDF]

, 1956
Jerome A. Urban
openalex   +1 more source